Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.74 |
| ▸ | TERT | O14746 | 2/20 | 0.74 |
| ▸ | APAF1 | O14727 | 2/20 | 0.69 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 2/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11443324 | 1.00 | APP (0.74) | APPTERTAPAF1EGFRALDH1A1 | |
| Hydrochloric Acid SCHEMBL2478442 | 0.98 | APP (0.71) | APPTERTAPAF1EGFRALDH1A1 | |
| SCHEMBL9276222 | 0.89 | APAF1 (0.64) | APPTERTAPAF1EGFRALDH1A1 | |
| SCHEMBL11437884 | 0.88 | APAF1 (0.67) | APPTERTAPAF1EGFRALDH1A1 | |
| Perchlorate SCHEMBL2477884 | 0.88 | APP (0.59) | APPTERTAPAF1EGFRALDH1A1 | |
| Hydrochloric Acid SCHEMBL28355349 | 0.86 | APAF1 (0.65) | APPTERTAPAF1EGFRALDH1A1 | |
| Hydrochloric Acid SCHEMBL11146532 | 0.86 | APAF1 (0.65) | APPTERTAPAF1EGFRALDH1A1 | |
| Acridine Orange SCHEMBL29361720 | 0.85 | TERT (1.00) | APPTERTAPAF1EGFRALDH1A1 | |
| Acridine Orange SCHEMBL297155 | 0.85 | TERT (1.00) | APPTERTAPAF1EGFRALDH1A1 | |
| Hydrochloric Acid SCHEMBL2475899 | 0.84 | TERT (0.65) | APPTERTAPAF1EGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891182-B1 | ENZYME ASSISTED DYEING OF KERATINOUS FIBRES | NOVOZYMES AS (DK) | 2001-11-14 | — | — | EP | claimed |
| EP-0863950-B1 | HAIR DYEING COMPOSITION | NOVOZYMES AS (DK) | 2001-10-10 | — | — | EP | claimed |
| EP-0865465-B1 | LACCASES WITH IMPROVED DYEING PROPERTIES | NOVOZYMES AS (DK) | 2001-05-30 | — | — | EP | claimed |
| EP-0973875-B1 | STORAGE-STABLE LIQUID FORMULATION COMPRISING A LACCASE | NOVOZYMES AS (DK) | 2006-06-14 | — | — | EP | disclosed |
| EP-1137391-B1 | METHOD FOR TREATING HAIR | NOVOZYMES AS (DK) | 2004-11-03 | — | — | EP | disclosed |
| US-6667167-B1 | Containing a polyalcohol such as a polyoxyalkylene glycol or ether, and a mono-, di-, oligo- or polysaccharides; pH that is more alkaline than the pH optimum of the laccase. | NOVOZYMES A/S (DK) | 2003-12-23 | — | — | US | disclosed |
| US-6572843-B1 | Combining permanent dyeing and straightening; applying to reduced hair an oxidizing enzyme (Laccase), a mediator, and a chemical oxidizing agent that produces hydrogen peroxide | NOVOZYMES, A/S (DK) | 2003-06-03 | — | — | US | disclosed |
| EP-1076494-B1 | RE-FORMATION OF KERATINOUS FIBRE CROSS LINKS | NOVOZYMES AS (DK) | 2002-09-18 | — | — | EP | disclosed |
| US-20020007524-A1 | Contacting fibers in a dry state with an oxidoreductase and a dye precursor; reduced hair damage | NOVOZYMES A/S (DK) | 2002-01-24 | — | — | US | disclosed |
| EP-0891182-B1 | ENZYME ASSISTED DYEING OF KERATINOUS FIBRES | NOVOZYMES AS (DK) | 2001-11-14 | — | — | EP | disclosed |
| EP-0863950-B1 | HAIR DYEING COMPOSITION | NOVOZYMES AS (DK) | 2001-10-10 | — | — | EP | disclosed |
| EP-0865465-B1 | LACCASES WITH IMPROVED DYEING PROPERTIES | NOVOZYMES AS (DK) | 2001-05-30 | — | — | EP | disclosed |
| US-6136578-A | LACCASE FROM POLYPORUS WITH AT LEAST ONE POLYALCOHOL AT A CONCENTRATION OF 5 TO 75 PERCENT; PH IS HIGHER THAN OPTIMUM OF THE ENZYME; FOR HAIR DYES, BLEACHING, AND DYEING OF FABRICS | NOVO NORDISK A/S (DK) | 2000-10-24 | — | — | US | disclosed |
| EP-1014921-A1 | ENZYMATIC FOAM COMPOSITIONS FOR DYEING KERATINOUS FIBRES | NOVO NORDISK A/S (DK) | 2000-07-05 | — | — | EP | disclosed |
| US-5948121-A | PERMANENT DYEING OF KERATINOUS FIBERS. LACCASE DERIVED FROM A STRAIN OF THE GENUS MYCELIOPHTHORA | NOVO NORDISK A/S (DK) | 1999-09-07 | — | — | US | disclosed |
| US-5899212-A | CLEAVAGE OF DISULFIDE BONDS, OXIDOREDUCTASE | NOVO NORDISK A/S (DK) | 1999-05-04 | — | — | US | disclosed |
| WO-1999015137-A1 | ENZYMATIC FOAM COMPOSITIONS FOR DYEING KERATINOUS FIBRES | NOVO NORDISK A/S (DK) | 1999-04-01 | — | — | WO | disclosed |
| US-4230784-A | Electrostatic image forming process and particles comprising reactive sublimable dye, subliming developer and conductive substance | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1980-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007524-A1 | Contacting fibers in a dry state with an oxidoreductase and a dye precursor; reduced hair damage | KRT18, CYB5R3, ADH7 | APP 1586/4885TERT 1562/4885APAF1 3079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.