Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26789531 | 0.82 | ALDH1A1 (0.51) | SMN1; SMN2HPGDHSD17B10LMNATSHR | |
| SCHEMBL7532501 | 0.75 | PKM (0.56) | SMN1; SMN2LMNAHTTALDH1A1PKM | |
| SCHEMBL17520146 | 0.75 | MAPT (0.41) | SMN1; SMN2LMNAHTTL3MBTL1ALDH1A1 | |
| SCHEMBL26792358 | 0.75 | LMNA (0.45) | SMN1; SMN2HPGDHSD17B10LMNATSHR | |
| SCHEMBL26789536 | 0.73 | LMNA (0.53) | SMN1; SMN2LMNATSHRADORA3L3MBTL1 | |
| SCHEMBL13304014 | 0.72 | HTT (0.49) | SMN1; SMN2HPGDHSD17B10LMNATSHR | |
| SCHEMBL30601583 | 0.72 | HTT (0.49) | SMN1; SMN2HPGDHSD17B10LMNATSHR | |
| SCHEMBL26789816 | 0.72 | POLB (0.40) | SMN1; SMN2HPGDTSHRHTTADORA3 | |
| SCHEMBL27651704 | 0.71 | ALDH1A1 (0.42) | SMN1; SMN2HSD17B10LMNATSHRHTT | |
| SCHEMBL19150881 | 0.71 | ADORA3 (0.46) | SMN1; SMN2HPGDHSD17B10HTTADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220247-A1 | LRRK2 INHIBITORS | INTERLINE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |