Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.62 |
| ▸ | TACR2 | P21452 | 1/20 | 0.59 |
| ▸ | FDPS | P14324 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255761 | 0.93 | FDPS (0.64) | ALDH1A1TACR2FDPSMAPTHPGD | |
| SCHEMBL31160627 | 0.93 | FDPS (0.64) | ALDH1A1TACR2FDPSMAPTHPGD | |
| SCHEMBL493684 | 0.90 | ALDH1A1 (0.73) | ALDH1A1TACR2FDPSMAPTHPGD | |
| SCHEMBL30159697 | 0.90 | ALDH1A1 (0.73) | ALDH1A1TACR2FDPSMAPTHPGD | |
| SCHEMBL28927694 | 0.87 | TACR2 (0.64) | ALDH1A1TACR2FDPSMAPTHPGD | |
| SCHEMBL4996828 | 0.87 | ALDH1A1 (0.56) | ALDH1A1TACR2FDPSMAPTHPGD | |
| SCHEMBL2850023 | 0.87 | FDPS (0.75) | ALDH1A1FDPSMAPTHPGDL3MBTL1 | |
| SCHEMBL3394561 | 0.87 | ALDH1A1 (0.70) | ALDH1A1FDPSMAPTHPGDTDP1 | |
| SCHEMBL31054299 | 0.87 | FDPS (0.75) | ALDH1A1FDPSMAPTHPGDL3MBTL1 | |
| SCHEMBL12758741 | 0.86 | FDPS (0.60) | ALDH1A1TACR2FDPSMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023118961-A1 | ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF | INTOCELL, INC. (KR) | 2023-06-29 | — | — | WO | disclosed |
| US-20230190939-A1 | ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF | INTOCELL, INC. (KR) | 2023-06-22 | — | — | US | disclosed |
| US-20230190939-A1 | ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF | INTOCELL, INC. (KR) | 2023-06-22 | — | — | US | disclosed |
| US-9394268-B2 | (E)-1-(5-methoxy-2,2-dimethyl-2H-chromen-8-yl)-3-(4-methoxyphenyl)prop-2-en-1-one and analogs thereof, as well as preparation method and use thereof | SICHUAN UNIVERSITY (CN) | 2016-07-19 | — | — | US | disclosed |
| US-9394268-B2 | (E)-1-(5-methoxy-2,2-dimethyl-2H-chromen-8-yl)-3-(4-methoxyphenyl)prop-2-en-1-one and analogs thereof, as well as preparation method and use thereof | SICHUAN UNIVERSITY (CN) | 2016-07-19 | — | — | US | disclosed |
| US-20150133659-A1 | (E)-1-(5-METHOXY-2,2-DIMETHYL-2H-CHROMEN-8-YL)-3-(4-METHOXYPHENYL)PROP-2-EN-1-ONE AND ANALOGS THEREOF, AS WELL AS PREPARATION METHOD AND USE THEREOF | SICHUAN UNIVERSITY (CN) | 2015-05-14 | — | — | US | disclosed |
| US-20150133659-A1 | (E)-1-(5-METHOXY-2,2-DIMETHYL-2H-CHROMEN-8-YL)-3-(4-METHOXYPHENYL)PROP-2-EN-1-ONE AND ANALOGS THEREOF, AS WELL AS PREPARATION METHOD AND USE THEREOF | SICHUAN UNIVERSITY (CN) | 2015-05-14 | — | — | US | disclosed |
| US-20120115128-A1 | SELECTIVE PROTEIN LABELING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (IL) | 2012-05-10 | — | — | US | disclosed |
| US-20120115128-A1 | SELECTIVE PROTEIN LABELING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (IL) | 2012-05-10 | — | — | US | disclosed |
| US-20120115128-A1 | SELECTIVE PROTEIN LABELING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (IL) | 2012-05-10 | — | — | US | disclosed |
| WO-2010129929-A1 | SELECTIVE PROTEIN LABELING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190939-A1 | ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF | CD47, ENPP2, CD2 | ALDH1A1 4468/4885TACR2 2371/4885FDPS 2576/4885 |
| US-20150133659-A1 | (E)-1-(5-METHOXY-2,2-DIMETHYL-2H-CHROMEN-8-YL)-3-(4-METHOXYPHENYL)PROP-2-EN-1-ONE AND ANALOGS THEREOF, AS WELL AS PREPARATION METHOD AND USE THEREOF | ECE1, CMA1, MME | ALDH1A1 207/4885TACR2 3828/4885FDPS 887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.