Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | PGK2 | P07205 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 8/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 4/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4832407 | 0.94 | KDM4E (0.44) | KDM4ECYP3A4MAPTPGK1PGK2 | |
| Hydrochloric Acid SCHEMBL5705745 | 0.92 | KDM4E (0.48) | KDM4ECYP3A4MAPTPGK1PGK2 | |
| SCHEMBL22446844 | 0.91 | NOS1 (0.39) | KDM4ECYP3A4MAPTPGK1PGK2 | |
| SCHEMBL13339967 | 0.88 | KDM4E (0.52) | KDM4ECYP3A4MAPTLOXL2PRMT6 | |
| SCHEMBL23265420 | 0.84 | ALDH1A1 (0.52) | KDM4ECYP3A4MAPTLOXL2NOS1 | |
| SCHEMBL11983503 | 0.84 | NOS1 (0.43) | KDM4ECYP3A4MAPTLOXL2NOS1 | |
| SCHEMBL6907497 | 0.84 | TACR1 (0.38) | KDM4ECYP3A4MAPTLOXL2PRMT6 | |
| Hydrochloric Acid SCHEMBL6913331 | 0.82 | KDM4E (0.40) | KDM4ECYP3A4MAPTLOXL2PRMT6 | |
| SCHEMBL12765145 | 0.80 | NOS1 (0.43) | NOS1NOS3NOS2 | |
| SCHEMBL14043315 | 0.80 | TSHR (0.43) | KDM4ENOS1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381327-A1 | REACTIVE CONJUGATES | DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381327-A1 | REACTIVE CONJUGATES | FCGR3B, FCGR1A, FCGR2A | KDM4E 3268/4885CYP3A4 2290/4885MAPT 66/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.