Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.68 |
| ▸ | NPC1 | O15118 | 8/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 2/20 | 0.58 |
| ▸ | NSD2 | O96028 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.53 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19330719 | 0.88 | NSD2 (0.58) | RAB9ANPC1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL11055398 | 0.84 | MAPT (0.56) | RAB9ANPC1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL17910004 | 0.84 | RAB9A (0.57) | RAB9ANPC1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL3731059 | 0.83 | NPC1 (0.55) | RAB9ANPC1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL10347621 | 0.83 | MAPT (0.55) | RAB9ANPC1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL13604179 | 0.82 | RAB9A (0.77) | RAB9ANPC1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL14087506 | 0.80 | RAB9A (0.60) | RAB9ANPC1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL26802269 | 0.80 | MAPT (0.51) | RAB9ANPC1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL12369468 | 0.79 | HCAR3 (0.76) | RAB9ANPC1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8311808 | 0.78 | RAB9A (0.56) | RAB9ANPC1KDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381327-A1 | REACTIVE CONJUGATES | DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381327-A1 | REACTIVE CONJUGATES | FCGR3B, FCGR1A, FCGR2A | RAB9A 267/4885NPC1 1404/4885KDM4E 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.