Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.39 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26802184 | 0.81 | HCAR3 (0.54) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL26803906 | 0.80 | MAPT (0.41) | NPC1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL27800469 | 0.73 | HDAC3 (0.36) | NPC1RAB9ASMN1; SMN2MAPTCTNNB1 | |
| SCHEMBL26802269 | 0.73 | MAPT (0.51) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL27601679 | 0.73 | HDAC3 (0.38) | NPC1RAB9ASMN1; SMN2MAPTHDAC3 | |
| SCHEMBL2608492 | 0.72 | HDAC3 (0.61) | NPC1RAB9ASMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL26807042 | 0.72 | CTNNB1 (0.35) | NPC1RAB9ASMN1; SMN2CTNNB1TCF7L2 | |
| SCHEMBL11138777 | 0.71 | HDAC3 (0.59) | NPC1RAB9ASMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL16831705 | 0.70 | HCAR3 (0.57) | NPC1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL26802263 | 0.68 | HDAC3 (0.51) | NPC1RAB9ASMN1; SMN2MAPTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381327-A1 | REACTIVE CONJUGATES | DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381327-A1 | REACTIVE CONJUGATES | FCGR3B, FCGR1A, FCGR2A | NPC1 1404/4885RAB9A 267/4885SMN1; SMN2 1890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.