Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.39 |
| ▸ | DRD1 | P21728 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11338231 | 0.82 | CYP2D6 (0.47) | CYP2D6CYP2C19LIPECHRM2ADRA2A | |
| SCHEMBL6988798 | 0.81 | CYP2D6 (0.46) | CYP2D6CYP2C19LIPECHRM2ADRA2A | |
| SCHEMBL9753625 | 0.79 | CA12 (0.53) | CYP2D6CYP2C19LIPECHRM2ADRA2A | |
| SCHEMBL2741387 | 0.79 | MGLL (0.53) | CYP2D6CYP2C19LIPECHRM2ADRA2A | |
| SCHEMBL9259760 | 0.78 | LMNA (0.55) | CYP2D6CYP2C19LIPECHRM2ADRA2A | |
| SCHEMBL12574808 | 0.78 | CYP2D6 (0.43) | CYP2D6CYP2C19LIPECHRM2ADRA2A | |
| SCHEMBL761923 | 0.77 | CYP2D6 (0.46) | CYP2D6CYP2C19LIPECHRM2ADRA2A | |
| SCHEMBL14273117 | 0.76 | HSP90AA1 (0.33) | SLC6A2POLBCHRM5 | |
| SCHEMBL762423 | 0.74 | ALDH1A1 (0.50) | CYP2D6CYP2C19LIPECHRM2ADRA2A | |
| SCHEMBL14344896 | 0.74 | CYP2D6 (0.47) | CYP2D6CYP2C19LIPECHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2450026-B1 | DENTAL COMPOSITION HAVING A REDOX INDICATOR AND METHOD OF USING SAME | KERR CORP (US) | 2023-03-15 | — | — | EP | disclosed |
| EP-2450027-B1 | DENTAL COMPOSITIONS HAVING SPECIAL FUNCTIONALITY AND TRI-BARREL PACKAGING | KERR CORP (US) | 2023-01-11 | — | — | EP | disclosed |
| US-9522099-B2 | Dental compositions having special functionality and a tri-barrel packaging and delivery system therefor | KERR CORPORATION (US) | 2016-12-20 | — | — | US | disclosed |
| US-9399004-B2 | Dental composition having a redox indicator and method of using same | KERR CORPORATION (US) | 2016-07-26 | — | — | US | disclosed |
| EP-1693046-B1 | Acid tolerant dental composition | KERR CORP (US) | 2015-07-01 | — | — | EP | disclosed |
| US-20120115978-A1 | DENTAL COMPOSITION HAVING A REDOX INDICATOR AND METHOD OF USING SAME | KERR CORPORATION (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120115106-A1 | DENTAL COMPOSITIONS HAVING SPECIAL FUNCTIONALITY AND A TRI-BARREL PACKAGING AND DELIVERY SYSTEM THEREFOR | KERR CORPORATION (US) | 2012-05-10 | — | — | US | disclosed |
| EP-2450026-A2 | Dental composition having a redox indicator and method of using same | Kerr Corporation (US) | 2012-05-09 | — | — | EP | disclosed |
| EP-2450027-A2 | Dental compositions having special functionality and a tri-barrel packaging and delivery system therefor | Kerr Corporation (US) | 2012-05-09 | — | — | EP | disclosed |
| US-7498367-B2 | Acid-tolerant dental composition | KERR CORPORATION (US) | 2009-03-03 | — | — | US | disclosed |
| US-20060189728-A1 | ACID-TOLERANT DENTAL COMPOSITION | KERR CORPORATION (US) | 2006-08-24 | — | — | US | disclosed |
| EP-1693046-A1 | Acid tolerant dental composition | Kerr Corporation (US) | 2006-08-23 | — | — | EP | disclosed |