Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | AHCY | P23526 | 3/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.43 |
| ▸ | GNMT | Q14749 | 1/20 | 0.42 |
| ▸ | AMD1 | P17707 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.41 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.41 |
| ▸ | GAPDH | P04406 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22337062 | 0.92 | ADORA1 (0.49) | ADORA1NT5EAHCYP2RY12GNMT | |
| SCHEMBL22337055 | 0.92 | ADORA1 (0.49) | ADORA1NT5EAHCYP2RY12GNMT | |
| SCHEMBL26808536 | 0.87 | ADORA3 (0.42) | ADORA1ADORA3ADORA2AADORA2BSLC29A1 | |
| SCHEMBL26808329 | 0.85 | ADORA1 (0.50) | ADORA1NT5EAHCYP2RY12GNMT | |
| SCHEMBL26808212 | 0.85 | ADORA1 (0.50) | ADORA1NT5EAHCYP2RY12GNMT | |
| SCHEMBL26808544 | 0.84 | LMNA (0.51) | ADORA1NT5EADORA3ADORA2AADORA2B | |
| SCHEMBL26808550 | 0.84 | PRMT6 (0.47) | ADORA1P2RY12ADORA3 | |
| SCHEMBL26808575 | 0.84 | SLC29A1 (0.38) | ADORA1ADORA3ADORA2AADORA2BSLC29A1 | |
| SCHEMBL26808594 | 0.83 | HINT1 (0.48) | NT5E | |
| SCHEMBL19941882 | 0.82 | ATM (0.48) | ADORA1NT5EAHCYP2RY12DOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357306-A1 | SYNTHESIS OF 1,2,5-TRI-O-BENZOYL-3-DIBENZYLAMINO-3-DEOXYRIBOSE AS INTERMEDIATE FOR PRODUCING 3'-AMINO-3'-DEOXYADENOSINE AND 3'-AMINO-3'-DEOXYGUANOSINE AND THE PROTECTED DERIVATIVES THEREOF | BRISTOL MYERS SQUIBB CO (US) | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357306-A1 | SYNTHESIS OF 1,2,5-TRI-O-BENZOYL-3-DIBENZYLAMINO-3-DEOXYRIBOSE AS INTERMEDIATE FOR PRODUCING 3'-AMINO-3'-DEOXYADENOSINE AND 3'-AMINO-3'-DEOXYGUANOSINE AND THE PROTECTED DERIVATIVES THEREOF | STING1, CGAS, AMPD3 | ADORA1 69/4885NT5E 56/4885AHCY 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.