Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 8/20 | 0.51 |
| ▸ | CA1 | P00915 | 11/20 | 0.47 |
| ▸ | CA2 | P00918 | 11/20 | 0.47 |
| ▸ | CA12 | O43570 | 9/20 | 0.47 |
| ▸ | CA7 | P43166 | 8/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 8/20 | 0.47 |
| ▸ | CA9 | Q16790 | 7/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26815363 | 1.00 | PNMT (0.51) | PNMTCA1CA2CA12CA7 | |
| SCHEMBL26656355 | 0.80 | CA1 (0.51) | PNMTCA1CA2CA12CA7 | |
| SCHEMBL26656308 | 0.80 | CA1 (0.51) | PNMTCA1CA2CA12CA7 | |
| SCHEMBL15896885 | 0.74 | PNMT (0.47) | PNMTADRA2AADRA2BADRA2CBRD4 | |
| SCHEMBL13634392 | 0.72 | ADRA2A (0.46) | PNMTADRA2AADRA2BADRA2CBRD4 | |
| SCHEMBL15445210 | 0.70 | PNMT (0.44) | PNMTADRA2AADRA2BADRA2CBRD4 | |
| SCHEMBL22955423 | 0.70 | CREBBP (0.59) | PNMTADRA2AADRA2BADRA2CBRD4 | |
| SCHEMBL32673749 | 0.69 | CA1 (0.50) | PNMTCA1CA2CA12CA7 | |
| SCHEMBL30664965 | 0.66 | CA1 (0.61) | PNMTCA1CA2CA12CA7 | |
| SCHEMBL4230983 | 0.66 | CA1 (0.61) | PNMTCA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225162-A1 | ANTIVIRAL INDOLINYL COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-11-23 | — | — | WO | disclosed |