Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.51 |
| ▸ | CA2 | P00918 | 10/20 | 0.51 |
| ▸ | CA12 | O43570 | 8/20 | 0.51 |
| ▸ | CA7 | P43166 | 6/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.51 |
| ▸ | CA9 | Q16790 | 7/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.45 |
| ▸ | PNMT | P11086 | 6/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26656308 | 1.00 | CA1 (0.51) | CA1CA2CA12CA7CA14 | |
| SCHEMBL32673749 | 0.89 | CA1 (0.50) | CA1CA2CA12CA7CA14 | |
| SCHEMBL8179542 | 0.81 | PNMT (0.49) | CA1CA2CA12CA7CA14 | |
| SCHEMBL26810290 | 0.80 | PNMT (0.51) | CA1CA2CA12CA7CA14 | |
| SCHEMBL26815363 | 0.80 | PNMT (0.51) | CA1CA2CA12CA7CA14 | |
| SCHEMBL94115 | 0.73 | ESR2 (0.49) | CREBBPBRD4MAPT | |
| SCHEMBL7037554 | 0.73 | MAPT (0.42) | CA9CREBBPPNMTADRA2AADRA2B | |
| SCHEMBL8182857 | 0.72 | PNMT (0.57) | PNMTALDH1A1MEN1MAPTALOX15 | |
| SCHEMBL23246026 | 0.72 | GAA (0.44) | CA1CA2CA12CA7CA14 | |
| SCHEMBL32673908 | 0.72 | LMNA (0.42) | CA1CA2CA12CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12522582-B2 | Antiviral indolinyl compounds and uses thereof | GILEAD SCIENCES, INC. (US) | 2026-01-13 | — | — | US | disclosed |
| EP-4526289-A1 | ANTIVIRAL INDOLINYL COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2025-03-26 | — | — | EP | disclosed |
| CN-119546574-A | Antiviral indolinyl compounds and uses thereof | 吉利德科学公司 | 2025-02-28 | — | — | CN | disclosed |
| US-20240101529-A1 | ANTIVIRAL INDOLINYL COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. | 2024-03-28 | — | — | US | disclosed |
| WO-2023225162-A1 | ANTIVIRAL INDOLINYL COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023225162-A1 | ANTIVIRAL INDOLINYL COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240101529-A1 | ANTIVIRAL INDOLINYL COMPOUNDS AND USES THEREOF | MAVS, IRF3, EIF2AK2 | CA1 4587/4885CA2 3954/4885CA12 4604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.