SCHEMBL26812

SCHEMBL26812

[N-]=[N+]=NS(=O)(=O)c1ccc(Oc2ccc(S(=O)(=O)N=[N+]=[N-])cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 7/20 0.47
ALDH1A1 P00352 5/20 0.47
SMN1; SMN2 Q16637 8/20 0.42
LMNA P02545 7/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
TP53 P04637 1/20 0.42
MAPT P10636 1/20 0.42
TSHR P16473 1/20 0.42
XBP1 P17861 1/20 0.42
MAPK1 P28482 1/20 0.42
MDM2 Q00987 1/20 0.42
HSD17B10 Q99714 1/20 0.42
SOS1 Q07889 3/20 0.41
POLB P06746 1/20 0.38
F2 P00734 2/20 0.37
PRSS1 P07477 2/20 0.37
PRSS2 P07478 2/20 0.37
PRSS3 P35030 2/20 0.37
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22033289 0.94 HTT (0.42) HTTALDH1A1SMN1; SMN2LMNANPC1
SCHEMBL17705376 0.88 SOS1 (0.49) HTTSMN1; SMN2LMNASOS1CA1
SCHEMBL10823807 0.87 CA1 (0.43) HTTALDH1A1LMNAMAPTF2
SCHEMBL4985580 0.87 HTT (0.38) HTTALDH1A1SMN1; SMN2LMNANPC1
SCHEMBL1683275 0.85 F2 (0.54) ALDH1A1NPC1RAB9AMAPTF2
SCHEMBL579486 0.84 CA12 (0.46) HTTALDH1A1TP53TSHRF2
SCHEMBL19891761 0.83 HTT (0.38) HTTALDH1A1SMN1; SMN2LMNANPC1
SCHEMBL19887231 0.81 EPAS1 (0.39) HTTALDH1A1SMN1; SMN2LMNAMAPT
SCHEMBL14281328 0.81 HTT (0.33) HTTALDH1A1SMN1; SMN2LMNANPC1
SCHEMBL5676376 0.81 CA2 (0.41) HTTSMN1; SMN2LMNAF2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583979-B2 Coupled post-consumer recycled polypropylene and process to provide same DOW GLOBAL TECHNOLOGIES LLC (US) 2026-03-24 US claimed
EP-3728457-B1 HIGH MELT FLOW RATE COUPLED IMPACT COPOLYMER WITH HIGH MELT STRENGTH BRASKEM AMERICA INC (US) 2026-02-18 EP claimed
US-20230167287-A1 HIGH MELT FLOW RATE COUPLED IMPACT COPOLYMER WITH HIGH MELT STRENGTH BRASKEM AMERICA, INC. (US) 2023-06-01 US claimed
EP-3990539-B1 COUPLED POST-CONSUMER RECYCLED POLYPROPYLENE AND PROCESS TO PROVIDE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2023-04-12 EP claimed
US-20220325051-A1 Coupled Post-Consumer Recycled Polypropylene and Process to Provide Same DOW GLOBAL TECHNOLOGIES LLC 2022-10-13 US claimed
EP-3990539-A1 COUPLED POST-CONSUMER RECYCLED POLYPROPYLENE AND PROCESS TO PROVIDE SAME Dow Global Technologies LLC (US) 2022-05-04 EP claimed
WO-2020263739-A1 COUPLED POST-CONSUMER RECYCLED POLYPROPYLENE AND PROCESS TO PROVIDE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2020-12-30 WO claimed
US-20190194436-A1 HIGH MELT FLOW RATE COUPLED IMPACT COPOLYMER WITH HIGH MELT STRENGTH BRASKEM AMERICA, INC. (US) 2019-06-27 US claimed
EP-2616511-B1 PROPYLENE-ALPHA-OLEFIN COPOLYMER COMPOSITIONS WITH IMPROVED FOAMING WINDOW DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-17 EP claimed
US-8883870-B2 Propylene-alpha-olefin copolymer compositions with improved foaming window DOW GLOBAL TECHNOLOGIES LLC (US) 2014-11-11 US claimed
US-20070125980-A1 Molecular melt and methods for making and using the molecular melt THE DOW CHEMICAL COMPANY 2007-06-07 US claimed
US-7141182-B2 Molecular melt and methods for making and using the molecular melt DOW GLOBAL TECHNOLOGIES INC. (US) 2006-11-28 US claimed
EP-1287065-B1 MOLECULAR MELT AND METHODS FOR MAKING AND USING THE MOLECULAR MELT DOW GLOBAL TECHNOLOGIES INC (US) 2006-03-01 EP claimed
US-20040181012-A1 Molecular melt and methods for making and using the molecular melt WALTERS MARLIN E (US) 2004-09-16 US claimed
EP-1287065-A2 MOLECULAR MELT AND METHODS FOR MAKING AND USING THE MOLECULAR MELT DOW GLOBAL TECHNOLOGIES INC. (US) 2003-03-05 EP claimed
US-20020052450-A1 Molecular melt and methods for making and using the molecular melt THE DOW CHEMICAL COMPANY 2002-05-02 US claimed
WO-2001083605-A2 MOLECULAR MELT AND METHODS FOR MAKING AND USING THE MOLECULAR MELT DOW GLOBAL TECHNOLOGIES INC. (US) 2001-11-08 WO claimed
EP-0133657-B1 THERMOPLASTIC COMPOSITION AND PROCESS GENERAL ELECTRIC COMPANY (US) 1991-10-23 EP claimed
US-4579905-A USING MULTIFUNCTIONAL GRAFT LINKING AGENT GENERAL ELECTRIC COMPANY (US) 1986-04-01 US claimed
US-RE30405-E Thermoplastic blend of partially cured monoolefin copolymer rubber and polyolefin plastic UNIROYAL, INC. (US) 1980-09-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583979-B2 Coupled post-consumer recycled polypropylene and process to provide same PPOX, SRMS, MVD HTT 2968/4885ALDH1A1 2223/4885SMN1; SMN2 2768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.