Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 2/20 | 0.46 |
| ▸ | ALPG | P10696 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | ALPP | P05187 | 1/20 | 0.46 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 3/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26817872 | 0.85 | LMNA (0.50) | LMNATSHRHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL26817860 | 0.76 | ATM (0.47) | LMNATSHRSMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL26817828 | 0.72 | TDP1 (0.50) | LMNAHTTSMN1; SMN2TNFALPL | |
| SCHEMBL3587930 | 0.72 | KDM4E (0.69) | LMNATSHRHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31498004 | 0.71 | TNF (0.64) | LMNATSHRHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4191641 | 0.71 | TNF (0.64) | LMNATSHRHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5252741 | 0.71 | LMNA (0.60) | LMNATSHRHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6446137 | 0.70 | LMNA (0.69) | LMNATSHRHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1104819 | 0.69 | TNF (0.66) | LMNATSHRHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL12497263 | 0.69 | LMNA (0.69) | LMNATSHRHTTSMN1; SMN2ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382946-A1 | POLYPEPTIDE OR PROTEIN DIRECTIONAL MODIFICATION METHOD BASED ON SULFHYDRYL-ALKENYL AZIDE COUPLING | Changzhou University (CN) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382946-A1 | POLYPEPTIDE OR PROTEIN DIRECTIONAL MODIFICATION METHOD BASED ON SULFHYDRYL-ALKENYL AZIDE COUPLING | PTMS, CBS, CHAMP1 | LMNA 4376/4885TSHR 1863/4885HTT 2090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.