SCHEMBL1104819

SCHEMBL1104819

CCn1c(C)nc2ccccc21

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNF P01375 1/20 0.66
HTT P42858 4/20 0.65
LMNA P02545 4/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
TSHR P16473 1/20 0.65
CYP1A2 P05177 1/20 0.65
CYP2D6 P10635 1/20 0.65
GALR3 O60755 3/20 0.62
NR2F2 P24468 3/20 0.62
RAB9A P51151 2/20 0.62
NPC1 O15118 1/20 0.62
PKM P14618 1/20 0.61
ALDH1A1 P00352 5/20 0.60
KDM4E B2RXH2 5/20 0.58
HPGD P15428 4/20 0.58
HSD17B10 Q99714 2/20 0.57
MAPK1 P28482 1/20 0.57
RAD52 P43351 1/20 0.57
TP53 P04637 2/20 0.57
MAPT P10636 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8009001 0.98 PKM (0.64) TNFHTTLMNASMN1; SMN2TSHR
SCHEMBL6446137 0.86 LMNA (0.69) TNFHTTLMNASMN1; SMN2TSHR
SCHEMBL230641 0.86 ALDH1A1 (0.70) HTTLMNASMN1; SMN2CYP1A2CYP2D6
SCHEMBL29430456 0.85 KDM4E (0.51) TNFHTTLMNASMN1; SMN2TSHR
SCHEMBL229041 0.85 POLB (0.67) TNFHTTLMNASMN1; SMN2TSHR
SCHEMBL4728183 0.82 TNF (0.64) TNFHTTLMNASMN1; SMN2TSHR
SCHEMBL4191641 0.82 TNF (0.64) TNFHTTLMNASMN1; SMN2TSHR
SCHEMBL11130492 0.82 TNF (0.64) TNFHTTLMNASMN1; SMN2TSHR
SCHEMBL31498004 0.82 TNF (0.64) TNFHTTLMNASMN1; SMN2TSHR
SCHEMBL1022300 0.82 TLR8 (0.69) TNFHTTLMNASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119661817-A Synthetic method of liquid crystal polyarylester and application of high-boiling-point imidazole catalyst in synthesis of liquid crystal polyarylester 浙江聚领新材料有限公司 2025-03-21 CN claimed
EP-2585473-B1 METAL PHOSPHONATE FLAME RETARDANT AND METHOD PRODUCING THEREOF ICL IP AMERICA INC (US) 2015-09-23 EP claimed
US-8889773-B2 Metal phosphonate flame retardant and method producing thereof ICL-IP AMERICA INC. (US) 2014-11-18 US claimed
US-20130165564-A1 METAL PHOSPHONATE FLAME RETARDANT AND METHOD PRODUCING THEREOF ICL-IP AMERICA INC. (US) 2013-06-27 US claimed
WO-2013077989-A1 PROCESS FOR PREPARATION OF ALUMINUM SALT OF PHOSPHONIC ACID ESTER ICL-IP AMERICA INC. (US) 2013-05-30 WO claimed
EP-2585473-A2 METAL PHOSPHONATE FLAME RETARDANT AND METHOD PRODUCING THEREOF ICL-IP America Inc. (US) 2013-05-01 EP claimed
WO-2011163207-A2 METAL PHOSPHONATE FLAME RETARDANT AND METHOD PRODUCING THEREOF ICL-IP AMERICA INC. (US) 2011-12-29 WO claimed
US-4542394-A MULTILAYER-DIAZONIUM LAYER AND COUPLER LAYER CONTAINING BENZIMIDAZOLE COMPOUND RICOH COMPANY, LTD. (JP) 1985-09-17 US claimed
EP-0075174-B1 PROCESS FOR THE PREPARATION OF 4-NITRODIPHENYL AMINES BAYER AG (DE) 1985-08-07 EP claimed
US-4404400-A REACTION OF AN ANILINE WITH A HALOGENONITROBENZENE BAYER AKTIENGESELLSCHAFT (DE) 1983-09-13 US claimed
EP-0075174-A1 Process for the preparation of 4-nitrodiphenyl amines BAYER AG (DE) 1983-03-30 EP claimed
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor BRILLIANT LIGHT POWER, INC. (US) 2026-02-03 US disclosed
CN-119661817-A Synthetic method of liquid crystal polyarylester and application of high-boiling-point imidazole catalyst in synthesis of liquid crystal polyarylester 浙江聚领新材料有限公司 2025-03-21 CN disclosed
WO-2024059665-A1 DIMERIC COMPOUNDS AS INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF MAZE THERAPEUTICS, INC. (US) 2024-03-21 WO disclosed
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF SUNDANCE BIOSCIENCES, INC. 2024-01-25 US disclosed
EP-0075174-B1 PROCESS FOR THE PREPARATION OF 4-NITRODIPHENYL AMINES BAYER AG (DE) 1985-08-07 EP disclosed
US-4404400-A REACTION OF AN ANILINE WITH A HALOGENONITROBENZENE BAYER AKTIENGESELLSCHAFT (DE) 1983-09-13 US disclosed
EP-0075174-A1 Process for the preparation of 4-nitrodiphenyl amines BAYER AG (DE) 1983-03-30 EP disclosed
US-4223087-A TREATING SURFACE WITH SOLUTION OF A FERRICYANIDE ANION AND A COMPLEXING AGENT; OXIDATION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1980-09-16 US disclosed
US-4204868-A PHOTOLITHOGRAPHY OLEOPHILIC SILVER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1980-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor SCO2, SOD1, HAO2 TNF 3422/4885HTT 2248/4885LMNA 4529/4885
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF TYK2, JAK1, JAK3 TNF 1646/4885HTT 1067/4885LMNA 4294/4885
US-20130165564-A1 METAL PHOSPHONATE FLAME RETARDANT AND METHOD PRODUCING THEREOF MTAP, AS3MT, MPHOSPH6 TNF 4072/4885HTT 3052/4885LMNA 3683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.