Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 2/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 2/20 | 0.44 |
| ▸ | ALPG | P10696 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26817876 | 0.86 | EGLN3 (0.56) | TDP1KDM4ELMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL26817874 | 0.84 | TDP1 (0.53) | TDP1NPC1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL7160203 | 0.77 | TDP1 (0.61) | TDP1KDM4ENPC1LMNASMN1; SMN2 | |
| SCHEMBL26818584 | 0.75 | KDM4E (0.60) | TDP1KDM4ENPC1LMNASMN1; SMN2 | |
| SCHEMBL7732690 | 0.75 | TDP1 (0.59) | TDP1KDM4ENPC1LMNASMN1; SMN2 | |
| SCHEMBL2882482 | 0.75 | TDP1 (0.59) | TDP1KDM4ENPC1LMNASMN1; SMN2 | |
| SCHEMBL11498670 | 0.75 | KDM4E (0.56) | TDP1KDM4ENPC1LMNASMN1; SMN2 | |
| SCHEMBL8017568 | 0.73 | TDP1 (0.56) | TDP1KDM4ENPC1LMNASMN1; SMN2 | |
| SCHEMBL26817834 | 0.72 | LMNA (0.50) | TDP1NPC1LMNASMN1; SMN2TNF | |
| SCHEMBL27864830 | 0.72 | TDP1 (0.63) | TDP1KDM4ENPC1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382946-A1 | POLYPEPTIDE OR PROTEIN DIRECTIONAL MODIFICATION METHOD BASED ON SULFHYDRYL-ALKENYL AZIDE COUPLING | Changzhou University (CN) | 2023-11-30 | — | — | US | disclosed |
| US-20230382946-A1 | POLYPEPTIDE OR PROTEIN DIRECTIONAL MODIFICATION METHOD BASED ON SULFHYDRYL-ALKENYL AZIDE COUPLING | Changzhou University (CN) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382946-A1 | POLYPEPTIDE OR PROTEIN DIRECTIONAL MODIFICATION METHOD BASED ON SULFHYDRYL-ALKENYL AZIDE COUPLING | PTMS, CBS, CHAMP1 | TDP1 4627/4885KDM4E 4700/4885NPC1 4725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.