SCHEMBL26831723

SCHEMBL26831723

CC(C)(C)c1ccc2c(c1)c1ccccc1n2-c1cccc(-n2c3ccc(C#N)cc3c3cc(C(C)(C)C)ccc32)c1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RORC P51449 9/20 0.40
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KIF11 P52732 2/20 0.39
PTGER4 P35408 2/20 0.36
CSNK1D P48730 2/20 0.36
CSNK1G2 P78368 2/20 0.36
PGR P06401 1/20 0.36
RORA P35398 1/20 0.36
RORB Q92753 1/20 0.36
GRM2 Q14416 1/20 0.35
G6PD P11413 1/20 0.35
CSNK1A1 P48729 1/20 0.34
GSK3B P49841 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17424694 1.00 RORC (0.40) RORCKDM4EATML3MBTL1KIF11
SCHEMBL17424684 1.00 RORC (0.40) RORCKDM4EATML3MBTL1KIF11
SCHEMBL17424670 1.00 RORC (0.40) RORCKDM4EATML3MBTL1KIF11
SCHEMBL17424686 0.95 KIF11 (0.42) KIF11CSNK1DCSNK1G2GRM2G6PD
SCHEMBL29512139 0.89 KDM4E (0.48) RORCKDM4EATML3MBTL1PTGER4
SCHEMBL8739982 0.89 KDM4E (0.48) RORCKDM4EATML3MBTL1PTGER4
SCHEMBL29457590 0.89 KDM4E (0.48) RORCKDM4EATML3MBTL1PTGER4
SCHEMBL30198387 0.89 KDM4E (0.48) RORCKDM4EATML3MBTL1PTGER4
SCHEMBL17424698 0.89 KDM4E (0.48) RORCKDM4EATML3MBTL1PTGER4
SCHEMBL17424677 0.89 KDM4E (0.48) RORCKDM4EATML3MBTL1PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363268-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 US disclosed
US-20230363268-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230363268-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE AOX1, CYP1A1, CRY1 RORC 455/4885KDM4E 2677/4885ATM 3588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.