Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2801832 | 0.82 | TSHR (0.52) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL2519799 | 0.82 | TSHR (0.52) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL2683928 | 0.81 | CACNA2D1 (0.40) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL2683355 | 0.81 | TSHR (0.44) | MEN1KMT2AALDH1A1HTTSLC6A2 | |
| SCHEMBL2683823 | 0.80 | ACP3 (0.45) | ACP3MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29288277 | 0.80 | IDO1 (0.42) | MEN1KMT2ALMNAALDH1A1CACNA2D1 | |
| SCHEMBL17845069 | 0.78 | APP (0.48) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL10784527 | 0.78 | PTGS1 (0.49) | MEN1KMT2ATSHR | |
| SCHEMBL2198030 | 0.77 | KCNA5 (0.46) | LMNAALDH1A1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL15998414 | 0.77 | MEN1 (0.47) | ACP3MEN1KMT2AADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461501-A | Green method for high-selectivity synthesis of chalcone compounds | 温州大学 | 2021-10-01 | — | — | CN | disclosed |
| US-8168835-B2 | Method for preparing propargylic alcohol catalyzed by 2-morpholinoisobornane-10-thiol | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-05-01 | — | — | US | disclosed |
| US-20110295042-A1 | METHOD FOR PREPARING PROPARGYLIC ALCOHOL CATALYZED BY 2-MORPHOLINOISOBORNANE-10-THIOL | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110295042-A1 | METHOD FOR PREPARING PROPARGYLIC ALCOHOL CATALYZED BY 2-MORPHOLINOISOBORNANE-10-THIOL | GRHPR, ADH1C, ADH5 | ACP3 4748/4885MEN1 946/4885KMT2A 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.