Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | GLA | P06280 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26847318 | 0.89 | HSD11B1 (0.35) | KDM4ETSHRGFERALDH1A1GLA | |
| SCHEMBL24088144 | 0.88 | KDM4E (0.36) | KDM4ECXCR2TSHRGFERALDH1A1 | |
| SCHEMBL26847325 | 0.81 | KDM4E (0.56) | KDM4ETSHRALDH1A1GLAGAA | |
| SCHEMBL24087950 | 0.76 | KDM4E (0.36) | KDM4ETSHRALDH1A1GLAGAA | |
| SCHEMBL20339960 | 0.73 | KDM4E (0.38) | KDM4ECXCR2ALDH1A1GLAGAA | |
| SCHEMBL26847372 | 0.72 | SERPINH1 (0.43) | KDM4ETSHRALDH1A1GAAHPGD | |
| SCHEMBL20339475 | 0.72 | HSD11B1 (0.34) | KDM4ECXCR2HSD11B1 | |
| SCHEMBL20340015 | 0.70 | KDM4E (0.58) | KDM4ECXCR2TSHRALDH1A1GLA | |
| SCHEMBL26847297 | 0.69 | ALDH1A1 (0.44) | KDM4ETSHRGFERALDH1A1GAA | |
| SCHEMBL20340100 | 0.69 | CYP1A2 (0.47) | KDM4ETSHRALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381177-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381177-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | ACMSD, GLS, ALDH7A1 | KDM4E 1110/4885CXCR2 4864/4885TSHR 4829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.