Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19449300 | 0.76 | SOS1 (0.33) | — | |
| SCHEMBL31706996 | 0.70 | IKBKB (0.34) | TGFBR1ACVR1 | |
| SCHEMBL26684759 | 0.68 | ADORA3 (0.36) | HRH3ADORA2AADORA1 | |
| SCHEMBL20831435 | 0.64 | CCNA2 (0.36) | ADORA2AADORA1 | |
| SCHEMBL14002271 | 0.64 | KDM4E (0.33) | TGFBR1 | |
| SCHEMBL30845858 | 0.62 | NAMPT (0.42) | PARP1HRH3KCNH2 | |
| SCHEMBL29716001 | 0.61 | PDCD1 (0.41) | — | |
| SCHEMBL19707974 | 0.61 | SOS1 (0.31) | — | |
| SCHEMBL2790456 | 0.60 | BCAT2 (0.42) | ADORA2AADORA1 | |
| SCHEMBL19708238 | 0.60 | DPP4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217906-A1 | PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-16 | — | — | WO | disclosed |