Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 10/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.48 |
| ▸ | TSHR | P16473 | 8/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | NMT2 | O60551 | 1/20 | 0.46 |
| ▸ | NMT1 | P30419 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157768 | 0.73 | CTSD (0.60) | CTSDBACE1CLK4CYP1A2CYP3A4 | |
| SCHEMBL26857255 | 0.73 | CTSD (0.49) | CTSDBACE1CLK4CYP1A2CYP3A4 | |
| SCHEMBL11581679 | 0.73 | GPR3 (0.59) | BACE1CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL24108948 | 0.71 | RXFP1 (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL14189996 | 0.70 | MPO (0.58) | ALDH1A1CYP2C9LMNAHSD17B10USP2 | |
| SCHEMBL9861710 | 0.70 | LMNA (0.43) | CYP1A2TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL12575801 | 0.70 | MPO (0.58) | CYP1A2CYP2C19CYP2D6ALDH1A1CYP2C9 | |
| SCHEMBL24108914 | 0.70 | ADORA2A (0.42) | CLK4CYP1A2CYP3A4CYP2C19TSHR | |
| SCHEMBL20071974 | 0.69 | CYP1A2 (0.49) | CTSDBACE1CLK4CYP1A2CYP3A4 | |
| SCHEMBL11037218 | 0.68 | MCL1 (0.64) | CTSDBACE1CYP3A4CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365628-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365628-A1 | MACROCYCLIC IMMUNOMODULATORS | CD274, PDCD1, PDCD1LG2 | CTSD 2063/4885BACE1 2826/4885CLK4 3774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.