Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 11/20 | 0.70 |
| ▸ | GHSR | Q92847 | 12/20 | 0.60 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1788135 | 0.82 | HCAR1 (1.00) | HCAR1GHSRHCAR2 | |
| SCHEMBL2685812 | 0.82 | HCAR1 (0.67) | HCAR1GHSRHCAR2 | |
| SCHEMBL1787440 | 0.77 | HCAR1 (0.90) | HCAR1GHSRHCAR2 | |
| SCHEMBL1787550 | 0.75 | HCAR1 (1.00) | HCAR1GHSRHCAR2 | |
| SCHEMBL1787129 | 0.75 | GHSR (1.00) | HCAR1GHSR | |
| SCHEMBL1784919 | 0.74 | GHSR (0.87) | HCAR1GHSRHCAR2 | |
| SCHEMBL1788186 | 0.74 | GHSR (1.00) | HCAR1GHSRHCAR2 | |
| SCHEMBL1786292 | 0.73 | GHSR (0.84) | HCAR1GHSRHCAR2 | |
| SCHEMBL1784513 | 0.73 | GHSR (1.00) | HCAR1GHSRHCAR2 | |
| SCHEMBL1785784 | 0.72 | GHSR (1.00) | HCAR1GHSRHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115845-A1 | THERAPEUTIC AGENTS | ALLEN JACK MCQUEEN (GB) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115845-A1 | THERAPEUTIC AGENTS | GPR119, MC2R, MC4R | HCAR1 1153/4885GHSR 30/4885HCAR2 1883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.