Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912706 | 0.87 | KIF11 (0.41) | KIF11AGTR1LMNACYP1A2HTT | |
| SCHEMBL2686112 | 0.79 | KIF11 (0.64) | KIF11LMNAHTTKCNH2L3MBTL1 | |
| SCHEMBL1263153 | 0.78 | KIF11 (0.43) | KIF11AGTR1LMNACYP1A2HTT | |
| SCHEMBL5924883 | 0.73 | CA1 (0.41) | KIF11HTTNR3C2KCNH2POLB | |
| SCHEMBL15517406 | 0.73 | LMNA (0.40) | KIF11AGTR1LMNACYP1A2HTT | |
| Succinic Acid SCHEMBL8741640 | 0.72 | LMNA (0.40) | KIF11AGTR1LMNACYP1A2HTT | |
| SCHEMBL7147413 | 0.72 | HTR1A (0.43) | CYP1A2NR3C2NPSR1SMN1; SMN2 | |
| SCHEMBL1263157 | 0.72 | KIF11 (0.41) | KIF11AGTR1LMNACYP1A2HTT | |
| SCHEMBL7144168 | 0.72 | HTR1A (0.43) | CYP1A2NR3C2NPSR1SMN1; SMN2 | |
| SCHEMBL1132966 | 0.71 | AGTR1 (0.38) | KIF11AGTR1LMNACYP1A2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187913-B1 | Covalently crosslinked oligonucleotides, preparation method and synthon which is of use in the method | GENSET (FR) | 2001-02-13 | — | — | US | disclosed |