Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | GRM5 | P41594 | 3/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027718 | 0.82 | MAOA (0.61) | MAOAMAOBGRM5PRKCIMEN1 | |
| SCHEMBL7916500 | 0.79 | MAOA (0.59) | MAOAMAOBGRM5PRKCIMEN1 | |
| SCHEMBL24370055 | 0.79 | GRM5 (0.40) | GRM5MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7510226 | 0.76 | MAOA (0.52) | MAOAMAOBGRM5PRKCIMEN1 | |
| SCHEMBL7917387 | 0.74 | MEN1 (0.46) | MAOAMAOBGRM5PRKCIMEN1 | |
| SCHEMBL1274936 | 0.72 | MAOA (0.59) | MAOAMAOBPRKCIMEN1KMT2A | |
| SCHEMBL29673118 | 0.72 | MAOA (0.59) | MAOAMAOBPRKCIMEN1KMT2A | |
| SCHEMBL27843799 | 0.72 | MAOA (0.49) | MAOAMAOBGRM5PRKCIMEN1 | |
| SCHEMBL29726014 | 0.71 | CASP1 (0.59) | MAOAMAOBGRM5PRKCIHSD17B10 | |
| SCHEMBL423287 | 0.71 | CASP1 (0.59) | MAOAMAOBGRM5PRKCIHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382860-A1 | Bioactive Benzocycloheptene Analogues From Himachalenes and its Applications | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-11-30 | — | — | US | disclosed |
| US-20230382860-A1 | Bioactive Benzocycloheptene Analogues From Himachalenes and its Applications | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382860-A1 | Bioactive Benzocycloheptene Analogues From Himachalenes and its Applications | HK2, GPR119, PIK3CD | MAOA 1783/4885MAOB 1613/4885GRM5 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.