Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26694292 | 0.83 | RAB9A (0.43) | GRM5ALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL29569978 | 0.83 | RAB9A (0.43) | GRM5ALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL26862736 | 0.79 | MAOA (0.45) | GRM5ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5648628 | 0.78 | PGR (0.49) | GRM5ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL29570985 | 0.71 | ACHE (0.37) | GRM5ALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL26694311 | 0.71 | ACHE (0.37) | GRM5ALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL6992256 | 0.69 | ALDH1A1 (0.42) | GRM5ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8807738 | 0.66 | MEN1 (0.49) | GRM5ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL28517437 | 0.66 | METAP1 (0.42) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL31106550 | 0.66 | METAP1 (0.42) | ALDH1A1MEN1KMT2AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382860-A1 | Bioactive Benzocycloheptene Analogues From Himachalenes and its Applications | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-11-30 | — | — | US | disclosed |
| US-20230382860-A1 | Bioactive Benzocycloheptene Analogues From Himachalenes and its Applications | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-11-30 | — | — | US | disclosed |
| WO-2022085023-A1 | BIOACTIVE BENZOCYCLOHEPTENE ANALOGUES FROM HIMACHALENES AND ITS APPLICATIONS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382860-A1 | Bioactive Benzocycloheptene Analogues From Himachalenes and its Applications | HK2, GPR119, PIK3CD | GRM5 305/4885ALDH1A1 2168/4885MEN1 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.