Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.39 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30667773 | 1.00 | LMNA (0.40) | LMNAALDH1A1MAPTPIK3CDPIK3CA | |
| SCHEMBL16505765 | 0.78 | LMNA (0.51) | LMNAALDH1A1MAPTSCN9APIM1 | |
| SCHEMBL28051826 | 0.72 | SCN9A (0.53) | SCN9AALOX5SLC13A5JAK1JAK3 | |
| SCHEMBL26684723 | 0.71 | LMNA (0.42) | LMNASCN9APIM1PIM3PIM2 | |
| SCHEMBL31507488 | 0.71 | LMNA (0.42) | LMNASCN9APIM1PIM3PIM2 | |
| SCHEMBL28051827 | 0.70 | SCN9A (0.39) | ALDH1A1MAPTSCN9AALOX5JAK1 | |
| SCHEMBL3662335 | 0.70 | FYN (0.47) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL18422297 | 0.69 | ALDH1A1 (0.44) | ALDH1A1MAPTPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3344435 | 0.69 | PKMYT1 (0.47) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL17130073 | 0.69 | HAVCR2 (0.40) | ALDH1A1MAPTABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217906-A1 | PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-16 | — | — | WO | disclosed |