Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2686402 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHRAKR1C3APPFBP1 | |
| SCHEMBL11360356 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRAKR1C3FBP1NPC1 | |
| SCHEMBL11203086 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TSHRAKR1C3FBP1NPC1 | |
| SCHEMBL11203090 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TSHRAKR1C3FBP1NPC1 | |
| SCHEMBL14626584 | 0.71 | ALDH1A1 (0.48) | ALDH1A1TSHRAKR1C3FBP1NPC1 | |
| SCHEMBL14626760 | 0.71 | ALDH1A1 (0.48) | ALDH1A1TSHRAKR1C3FBP1NPC1 | |
| SCHEMBL19732123 | 0.70 | NPC1 (0.51) | ALDH1A1TSHRAKR1C3FBP1NPC1 | |
| SCHEMBL28563539 | 0.70 | ALDH1A1 (0.52) | ALDH1A1TSHRAKR1C3FBP1NPC1 | |
| SCHEMBL1657799 | 0.69 | APP (0.50) | ALDH1A1APPNPC1RAB9ALMNA | |
| SCHEMBL1657802 | 0.69 | APP (0.50) | ALDH1A1APPNPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168835-B2 | Method for preparing propargylic alcohol catalyzed by 2-morpholinoisobornane-10-thiol | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-05-01 | — | — | US | disclosed |
| US-20110295042-A1 | METHOD FOR PREPARING PROPARGYLIC ALCOHOL CATALYZED BY 2-MORPHOLINOISOBORNANE-10-THIOL | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110295042-A1 | METHOD FOR PREPARING PROPARGYLIC ALCOHOL CATALYZED BY 2-MORPHOLINOISOBORNANE-10-THIOL | GRHPR, ADH1C, ADH5 | ALDH1A1 99/4885TSHR 290/4885AKR1C3 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.