SCHEMBL2686757

SCHEMBL2686757

COc1ccsc1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromobenzene SCHEMBL27629033 0.84 TDP1 (0.41)
SCHEMBL5317642 0.77 ACHE (0.57)
SCHEMBL5133848 0.76 KEAP1 (0.52)
SCHEMBL1141959 0.74
SCHEMBL12247683 0.73 KEAP1 (0.45)
SCHEMBL13283367 0.73
SCHEMBL765304 0.72 KDM4E (0.44)
SCHEMBL5610297 0.72
SCHEMBL28838159 0.72
SCHEMBL5154245 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400172-A2 PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS Incyte Holdings Corporation (US) 2024-07-17 EP disclosed
US-20240150340-A1 CDK Inhibitors And Their Use As Pharmaceuticals PRELUDE THERAPEUTICS INCORPORATED 2024-05-09 US disclosed
WO-2024077216-A1 CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS PRELUDE THERAPEUTICS INCORPORATED (US) 2024-04-11 WO disclosed
WO-2024077216-A1 CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS PRELUDE THERAPEUTICS INCORPORATED (US) 2024-04-11 WO disclosed
CN-112424181-B Substituted condensed thiophenes as STING modulators 希泰克斯特私人有限公司 2024-02-27 CN disclosed
US-11771738-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-03 US disclosed
US-11771738-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-03 US disclosed
WO-2023141511-A1 POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 VANDERBILT UNIVERSITY (US) 2023-07-27 WO disclosed
WO-2023081860-A1 TRIAZINE AMINO DERIVATIVES FOR TREATING SCA3 SKYHAWK THERAPEUTICS, INC. (US) 2023-05-11 WO disclosed
WO-2023049518-A1 BENZIMIDAZOLE CARBOXYLIC ACIDS AS GLP-1R AGONISTS TERNS PHARMACEUTICALS, INC. (US) 2023-03-30 WO disclosed
EP-0164227-B1 NEOALKOXY ORGANO-TITANATES AND ORGANO-ZIRCONATES USEFUL AS COUPLING AND POLYMER PROCESSING AGENTS KENRICH PETROCHEMICALS, INC. (US) 1990-08-16 EP disclosed
EP-0328983-A1 Highly soluble electrically conductive polymers HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-23 EP disclosed
EP-0328981-A2 Electrically conducting coating compound, process for its preparation and its use HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-23 EP disclosed
EP-0292905-A2 Electrically conductive coating composition, method for its manufacture and its use HOECHST AKTIENGESELLSCHAFT (DE) 1988-11-30 EP disclosed
EP-0257573-A1 Soluble electrically conductive polymers, method of producing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-03-02 EP disclosed
EP-0240137-A2 Repolymerization KENRICH PETROCHEMICALS, INC. (US) 1987-10-07 EP disclosed
US-4657988-A NEOALKOXY ZIRCONATE OR TITANATE ADDITIVES; ISOMERIZATION, REARRANGEMENT; POLYETHERS, POLYESTERS, POLYURETHANES KENRICH PETROCHEMICALS, INC. (US) 1987-04-14 US disclosed
US-4623738-A ANCHORING FILLER TO POLYMER KENRICH PETROCHEMICALS, INC. (US) 1986-11-18 US disclosed
US-4600789-A Neoalkoxy organo-titanate useful as coupling and polymer processing agents KENRICH PETROCHEMICALS, INC. (US) 1986-07-15 US disclosed
EP-0164227-A2 Neoalkoxy organo-titanates and organo-zirconates useful as coupling and polymer processing agents KENRICH PETROCHEMICALS, INC. (US) 1985-12-11 EP disclosed