SCHEMBL5154245

SCHEMBL5154245

COc1ccsc1N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28838159 0.75
SCHEMBL5133848 0.74 KEAP1 (0.52)
SCHEMBL5728055 0.73 KDM4E (0.43)
SCHEMBL1141959 0.72
SCHEMBL2686757 0.72
SCHEMBL28742962 0.72 ALDH1A1 (0.44)
SCHEMBL11808741 0.70 RAB9A (0.42)
SCHEMBL9035702 0.70
SCHEMBL5154547 0.70
SCHEMBL5610297 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7297168-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2007-11-20 US claimed
US-20050198745-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-09-15 US claimed
US-9227957-B2 Pesticidal pyrimidine compounds DOW AGROSCIENCES LLC (US) 2016-01-05 US disclosed
US-20150141446-A1 PESTICIDAL PYRIMIDINE COMPOUNDS CORTEVA AGRISCIENCE LLC 2015-05-21 US disclosed
US-8916578-B2 Pesticidal pyrimidine compounds DOW AGROSCIENCES, LLC. (US) 2014-12-23 US disclosed
US-20140221408-A1 PESTICIDAL PYRIMIDINE COMPOUNDS DOW AGROSCIENCES, LLC (US) 2014-08-07 US disclosed
US-8785465-B2 Pesticidal pyrimidine compounds Dow AgroSciences, L.L.C. (US) 2014-07-22 US disclosed
US-20140134271-A1 PESTICIDAL PYRIMIDINE COMPOUNDS DOW AGROSCIENCES LLC (US) 2014-05-15 US disclosed
US-7297168-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2007-11-20 US disclosed
CN-1913865-A Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE (US) 2007-02-14 CN disclosed
EP-1737417-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF The Procter and Gamble Company (US) 2007-01-03 EP disclosed
US-20050198745-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-09-15 US disclosed
WO-2005074875-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2005-08-18 WO disclosed
EP-0115394-B1 PHENOTHIAZONE DERIVATIVES AND ANALOGS MERCK FROSST CANADA INC. (CA) 1989-06-28 EP disclosed
EP-0115394-A2 Phenothiazone derivatives and analogs MERCK FROSST CANADA INC. (CA) 1984-08-08 EP disclosed
US-4263205-A FOR COLORING POLYMERS, LACQUERS CIBA-GEIGY CORPORATION (US) 1981-04-21 US disclosed
EP-0006154-A1 Monoazo pigments and their use in colouring high molecular-weight organic material CIBA-GEIGY AG (CH) 1980-01-09 EP disclosed