Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025506 | 0.80 | KMT2A (0.36) | KMT2AMEN1CYP1A2MAPTALDH1A1 | |
| SCHEMBL5728055 | 0.79 | KDM4E (0.43) | KDM4EHPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL29220005 | 0.79 | ACHE (0.45) | KDM4EHPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL12213171 | 0.79 | RAB9A (0.48) | KMT2ALMNANPSR1NPC1 | |
| SCHEMBL9026956 | 0.78 | GSK3B (0.35) | KMT2AMEN1CYP1A2SMN1; SMN2MAPT | |
| SCHEMBL28889801 | 0.78 | PLA2G10 (0.37) | KMT2AMEN1CYP1A2SMN1; SMN2MAPT | |
| SCHEMBL12213175 | 0.77 | KMT2A (0.34) | HSD17B10KMT2AMEN1CYP1A2SMN1; SMN2 | |
| SCHEMBL5728011 | 0.75 | KDM4E (0.44) | KDM4EHPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL28717530 | 0.75 | ALDH1A1 (0.41) | KDM4EHPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL27576766 | 0.74 | THRB (0.40) | HPGDKMT2AMEN1CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776011-B1 | FUNGICIDAL COMPOSITION CONTAINING AN ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-8039420-B2 | Fungicidal composition containing acid amide derivative | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2011-10-18 | — | — | US | disclosed |
| US-7829501-B2 | Fungicidal composition containing acid amide derivative | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-7829501-B2 | Fungicidal composition containing acid amide derivative | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20100261735-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
| US-20100261675-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
| US-20100261675-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
| US-20080318779-A1 | N-[(4'-methoxy-2'-methyl-1,1-dimethyl)phenacyl]-3-methyl-2-thiophenecarboxamide and another fungicide or an antibiotic; controlling noxious fungi at a low dose; Oomycetes, Ascomycetes, Basidiomycetes, Deuteromycetes particularly effective against Ascomycetes or Deuteromycetes; plant diseases | ISHIHARA SANGYO KAISHA LTD (JP) | 2008-12-25 | — | — | US | disclosed |
| US-20080318779-A1 | N-[(4'-methoxy-2'-methyl-1,1-dimethyl)phenacyl]-3-methyl-2-thiophenecarboxamide and another fungicide or an antibiotic; controlling noxious fungi at a low dose; Oomycetes, Ascomycetes, Basidiomycetes, Deuteromycetes particularly effective against Ascomycetes or Deuteromycetes; plant diseases | ISHIHARA SANGYO KAISHA LTD (JP) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318779-A1 | N-[(4'-methoxy-2'-methyl-1,1-dimethyl)phenacyl]-3-methyl-2-thiophenecarboxamide and another fungicide or an antibiotic; controlling noxious fungi at a low dose; Oomycetes, Ascomycetes, Basidiomycetes, Deuteromycetes particularly effective against Ascomycetes or Deuteromycetes; plant diseases | AADAC, NAT1, TH | KDM4E 683/4885HPGD 2005/4885HSD17B10 741/4885 |
| US-20100261675-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | CBR3, AADAC, NAT1 | KDM4E 1297/4885HPGD 786/4885HSD17B10 165/4885 |
| US-20100261735-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | CBR3, AADAC, NAT1 | KDM4E 1297/4885HPGD 786/4885HSD17B10 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.