Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.32 |
| ▸ | CDK1 | P06493 | 2/20 | 0.32 |
| ▸ | CDK4 | P11802 | 2/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.32 |
| ▸ | CCND1 | P24385 | 2/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CDK7 | P50613 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | CCNH | P51946 | 2/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.32 |
| ▸ | CDK3 | Q00526 | 2/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26870979 | 0.87 | KDM4E (0.36) | KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL26871243 | 0.86 | KDM4E (0.33) | KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL26873554 | 0.86 | KDM4E (0.36) | KDM4EALDH1A1MAPTRAB9ACCNT1 | |
| SCHEMBL26871082 | 0.75 | CDK2 (0.36) | KDM4EALDH1A1MAPTRAB9ACCNT1 | |
| SCHEMBL26870956 | 0.73 | PDE10A (0.53) | — | |
| SCHEMBL26873560 | 0.73 | CDK9 (0.63) | CCNT1CDK1CDK4CCNA2CCND1 | |
| SCHEMBL31465393 | 0.71 | KDM4E (0.59) | KDM4EALDH1A1MAPTRAB9ACCNT1 | |
| SCHEMBL12953072 | 0.70 | PDE10A (0.46) | KDM4EALDH1A1MAPTRAB9ACCNT1 | |
| SCHEMBL26869184 | 0.70 | KDM4E (0.36) | KDM4EALDH1A1MAPTRAB9ACCNA2 | |
| SCHEMBL12953015 | 0.68 | CDK2 (0.52) | KDM4EALDH1A1MAPTRAB9ACCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |