Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26873554 | 0.84 | KDM4E (0.36) | KDM4EMEN1NPC1KMT2AMAPT | |
| SCHEMBL26870979 | 0.83 | KDM4E (0.36) | KDM4EMEN1KMT2AMAPTRAB9A | |
| SCHEMBL26869154 | 0.81 | KDM4E (0.34) | KDM4ENPC1MAPTRAB9AMAPK1 | |
| SCHEMBL26868395 | 0.76 | PIM1 (0.36) | KDM4EMEN1NPC1KMT2AMAPT | |
| SCHEMBL26868111 | 0.76 | PIM1 (0.36) | KDM4EMEN1NPC1KMT2AMAPT | |
| SCHEMBL26871792 | 0.75 | CSNK2B (0.46) | KDM4EMEN1NPC1KMT2AMAPT | |
| SCHEMBL26871796 | 0.73 | CDK9 (0.48) | CYP1A2CCNA2CDK2CCNA1 | |
| SCHEMBL26869183 | 0.72 | KDM4E (0.40) | KDM4ENPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL26871218 | 0.70 | KDM4E (0.34) | KDM4EMAPTRAB9AALDH1A1CCNA2 | |
| SCHEMBL26871243 | 0.68 | KDM4E (0.33) | KDM4EMAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |