Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.33 |
| ▸ | CDK2 | P24941 | 4/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26871218 | 0.86 | KDM4E (0.34) | KDM4EMAPTRAB9AALDH1A1CCNA2 | |
| SCHEMBL26869184 | 0.84 | KDM4E (0.36) | KDM4EMEN1NPC1MAPTRAB9A | |
| SCHEMBL26873342 | 0.75 | CDK2 (0.36) | KDM4EMEN1NPC1MAPTRAB9A | |
| SCHEMBL26873560 | 0.74 | CDK9 (0.63) | CYP1A2CCNA2CDK2CCNA1CCNT1 | |
| SCHEMBL26870979 | 0.73 | KDM4E (0.36) | KDM4EMEN1MAPTRAB9AKMT2A | |
| SCHEMBL31465402 | 0.72 | MAPT (0.61) | KDM4EMEN1NPC1MAPTRAB9A | |
| SCHEMBL26871243 | 0.72 | KDM4E (0.33) | KDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL23242923 | 0.72 | MEN1 (0.42) | KDM4EMEN1NPC1MAPTRAB9A | |
| SCHEMBL26869183 | 0.71 | KDM4E (0.40) | KDM4ENPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL31465464 | 0.70 | KDM4E (0.41) | KDM4EMEN1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |