Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.41 |
| ▸ | CDK9 | P50750 | 6/20 | 0.41 |
| ▸ | CDK2 | P24941 | 4/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 3/20 | 0.39 |
| ▸ | CCND1 | P24385 | 3/20 | 0.39 |
| ▸ | CDK7 | P50613 | 3/20 | 0.39 |
| ▸ | CCNH | P51946 | 3/20 | 0.39 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.39 |
| ▸ | CDK3 | Q00526 | 2/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33377999 | 0.66 | CSNK2B (0.60) | CSNK2BRAB9AMEN1NPC1KMT2A | |
| SCHEMBL24174228 | 0.64 | CDK2 (0.50) | CSNK2BRAB9AMEN1NPC1KMT2A | |
| SCHEMBL11931171 | 0.63 | MAP3K5 (0.45) | CSNK2BCDK2GSK3BCCNA2 | |
| SCHEMBL1934608 | 0.62 | CSNK2B (1.00) | CSNK2BRAB9AMEN1NPC1KMT2A | |
| SCHEMBL22899497 | 0.62 | CDK2 (0.46) | CSNK2BRAB9AMEN1NPC1KMT2A | |
| SCHEMBL22899498 | 0.62 | RAB9A (0.51) | CSNK2BRAB9AMEN1NPC1KMT2A | |
| SCHEMBL21877782 | 0.61 | CCNT1 (0.95) | CCNT1CDK9CDK2CDK4CCND1 | |
| SCHEMBL24174230 | 0.61 | CDK9 (0.62) | CCNT1CDK9CDK2CDK4CCND1 | |
| SCHEMBL30083614 | 0.60 | KDR (0.38) | CSNK2BCDK2GSK3BKCNH2 | |
| SCHEMBL21877697 | 0.60 | CCNT1 (0.93) | CCNT1CDK9CDK2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |