Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 13/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 10/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 7/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 7/20 | 0.40 |
| ▸ | CDK7 | P50613 | 6/20 | 0.40 |
| ▸ | CDK1 | P06493 | 6/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.40 |
| ▸ | CDK4 | P11802 | 5/20 | 0.40 |
| ▸ | CCND1 | P24385 | 5/20 | 0.40 |
| ▸ | CCNH | P51946 | 5/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26871814 | 0.90 | CDK9 (0.44) | CSNK2BCDK9CCNT1RAB9AMEN1 | |
| SCHEMBL26869077 | 0.87 | CDK9 (0.38) | CDK9CCNT1CDK2CDK5CDK7 | |
| SCHEMBL26871754 | 0.86 | CDK9 (0.61) | CDK9CCNT1CDK2CDK5CDK7 | |
| SCHEMBL26871566 | 0.84 | RAB9A (0.47) | CSNK2BCDK9CCNT1RAB9AMEN1 | |
| SCHEMBL26871688 | 0.81 | CSNK2B (0.46) | CSNK2BCDK9CCNT1RAB9AMEN1 | |
| SCHEMBL26870935 | 0.79 | CDK2 (0.39) | CDK9CCNT1RAB9ACDK2CDK5 | |
| SCHEMBL26869093 | 0.79 | CHEK1 (0.52) | CDK9CCNT1RAB9AMEN1NPC1 | |
| SCHEMBL26871380 | 0.79 | CSNK2A1 (0.52) | CSNK2BCDK2CSNK2A1 | |
| SCHEMBL26872804 | 0.79 | CSNK2B (0.41) | CSNK2BCDK9CCNT1RAB9AMEN1 | |
| SCHEMBL26871818 | 0.76 | CDK9 (0.60) | CDK9CCNT1CDK2CDK5CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |