Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26870956 | 0.82 | PDE10A (0.53) | PDE10A | |
| SCHEMBL26868394 | 0.75 | CDK2 (0.46) | KDM4ECHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL26871783 | 0.73 | CDK9 (0.56) | CCNA2CDK2CCNA1 | |
| SCHEMBL26869184 | 0.72 | KDM4E (0.36) | KDM4ECHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL26871786 | 0.72 | CDK9 (0.62) | CCNA2CDK2CCNA1 | |
| SCHEMBL26873554 | 0.71 | KDM4E (0.36) | KDM4ECHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL4431791 | 0.71 | ALDH1A1 (0.50) | KDM4ECHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL17026690 | 0.70 | CDK2 (0.48) | CHEK1CCNA2CDK2CCNA1PDE10A | |
| SCHEMBL7847598 | 0.68 | CDK2 (0.44) | CHEK1CCNA2CDK2CCNA1PDE10A | |
| SCHEMBL14316241 | 0.67 | CDK2 (0.46) | KDM4ECHEK1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |