SCHEMBL2687634

SCHEMBL2687634

c1cnn(-c2nnn[nH]2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
KDM4E B2RXH2 3/20 0.38
LMNA P02545 3/20 0.38
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
G6PD P11413 1/20 0.38
KMT2A Q03164 1/20 0.38
NOTUM Q6P988 1/20 0.37
MAPK1 P28482 2/20 0.34
NPC1 O15118 1/20 0.34
TDO2 P48775 1/20 0.33
ADORA2A P29274 2/20 0.32
ADORA3 P0DMS8 1/20 0.32
ADORA2B P29275 1/20 0.32
ADORA1 P30542 1/20 0.32
HTT P42858 1/20 0.32
KDM4A O75164 1/20 0.30
KDM4B O94953 1/20 0.30
KDM5C P41229 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29224715 0.81 ACVR1B (0.40) ALDH1A1KDM4ELMNANPC1HTT
SCHEMBL9466419 0.74 NPC1 (0.33) MAPK1NPC1
SCHEMBL6355265 0.72 NOTUM (0.37) NOTUM
SCHEMBL8688771 0.68 KDM4E (0.35) ALDH1A1KDM4E
SCHEMBL6053126 0.67 KDM4E (0.37) ALDH1A1KDM4ELMNAMEN1GAA
SCHEMBL11143408 0.67 KDM4E (0.37) ALDH1A1KDM4ELMNAMEN1GAA
SCHEMBL17476686 0.66 KDM4E (0.48) ALDH1A1KDM4ELMNAMEN1GAA
SCHEMBL11153808 0.65 KDM4A (0.38) ALDH1A1KDM4ELMNAMEN1GAA
SCHEMBL11153631 0.65 ALDH1A1 (0.40) ALDH1A1KDM4ELMNAMEN1GAA
SCHEMBL308284 0.65 F2RL1 (0.41) ALDH1A1KDM4ELMNAMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1072430-B1 Ink jet printing process EASTMAN KODAK CO (US) 2005-12-14 EP claimed
US-6364476-B1 IMAGE-RECORDING LAYER INCLUDES A MIXTURE OF AN ANIONIC, ADDITION POLYMER AND A HYDROPHILIC POLYMER; INK INCLUDES WATER, HUMECTANT AND A WATER-SOLUBLE CATIONIC OR BASIC DYE; IMPROVED DYE DENSITY AND FIXABILITY EASTMAN KODAK COMPANY 2002-04-02 US claimed
EP-1153761-A2 Ink jet printing process EASTMAN KODAK COMPANY (US) 2001-11-14 EP claimed
US-6280027-B1 Ink jet printing process EASTMAN KODAK COMPANY 2001-08-28 US claimed
US-6280026-B1 Ink jet printing process EASTMAN KODAK COMPANY 2001-08-28 US claimed
US-6280028-B1 Ink jet printing process EASTMAN KODAK COMPANY 2001-08-28 US claimed
EP-1072430-A2 Ink jet printing process EASTMAN KODAK COMPANY (US) 2001-01-31 EP claimed
EP-1072431-A2 Ink jet printing process EASTMAN KODAK COMPANY (US) 2001-01-31 EP claimed
US-20250313567-A1 IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES AS A2A / A2B INHIBITORS INCYTE CORPORATION 2025-10-09 US disclosed
CN-115279766-B Combination therapy comprising A2A/A2B and a PD-1/PD-L1 inhibitor 因赛特公司 2025-05-02 CN disclosed
US-20250059293-A1 CD73 INHIBITOR AND A2A/A2B ADENOSINE RECEPTOR INHIBITOR COMBINATION THERAPY INCYTE CORPORATION 2025-02-20 US disclosed
US-20250041310-A1 Combination Therapy Comprising A2A/A2B and PD-1/PD-L1 Inhibitors INCYTE CORPORATION 2025-02-06 US disclosed
US-20250034153-A1 TRIAZOLOPYRIMIDINES AS A2A / A2B INHIBITORS INCYTE CORPORATION 2025-01-30 US disclosed
CN-112384515-B Imidazopyrimidines and triazolopyrimidines as A2A/A2B inhibitors 因赛特公司 2024-12-10 CN disclosed
US-5834171-A DEVELOPERS; STORAGE STABILITY KONICA CORPORATION (JP) 1998-11-10 US disclosed
EP-0785467-A1 Solid processing composition for silver halide photographic light sensitive material KONICA CORPORATION (JP) 1997-07-23 EP disclosed
US-5246914-A Fungicides and plant growth regulators BASF AKTIENGESELLSCHAFT (DE) 1993-09-21 US disclosed
EP-0087880-B1 SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1986-05-14 EP disclosed
US-4477561-A PLATIUM, DALLADIUM, RHODIUM, IRIDIUM AND OSMIUM SALTS; LIGHT SENSITIVE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-10-16 US disclosed
EP-0087880-A2 Silver halide photographic material KONICA CORPORATION (JP) 1983-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250059293-A1 CD73 INHIBITOR AND A2A/A2B ADENOSINE RECEPTOR INHIBITOR COMBINATION THERAPY ADORA2A, ADORA2B, NT5E ALDH1A1 565/4885KDM4E 3788/4885LMNA 2681/4885
US-20250041310-A1 Combination Therapy Comprising A2A/A2B and PD-1/PD-L1 Inhibitors ADORA2A, ADORA2B, ADORA1 ALDH1A1 187/4885KDM4E 3443/4885LMNA 2429/4885
US-20250034153-A1 TRIAZOLOPYRIMIDINES AS A2A / A2B INHIBITORS ADORA2A, ADORA2B, ADORA1 ALDH1A1 498/4885KDM4E 4413/4885LMNA 3689/4885
US-20250313567-A1 IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES AS A2A / A2B INHIBITORS ADORA2A, ADORA2B, ADORA1 ALDH1A1 347/4885KDM4E 4274/4885LMNA 4020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.