Sugi Predict

Sugi Predict / Compounds / SCHEMBL2687704

SCHEMBL2687704

SCHEMBL2687704

Cc1cccc(C(=N)N)c1

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ PARP1 P09874 1/20 0.63
▸ PRSS1 P07477 9/20 0.60
▸ PRSS2 P07478 7/20 0.60
▸ PRSS3 P35030 7/20 0.60
▸ C1S P09871 2/20 0.60
▸ F2 P00734 2/20 0.57
▸ PLG P00747 1/20 0.57
▸ NOS1 P29475 1/20 0.55
▸ LOXL2 Q9Y4K0 1/20 0.53
▸ F10 P00742 1/20 0.52
▸ F12 P00748 1/20 0.52
▸ F7 P08709 1/20 0.52
▸ F3 P13726 1/20 0.52
▸ PKM P14618 1/20 0.52
▸ BLM P54132 1/20 0.50
▸ HDAC8 Q9BY41 1/20 0.48
▸ HDAC6 Q9UBN7 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1436160 0.98 PRSS1 (0.61) PARP1PRSS1PRSS2PRSS3C1S
Hydrochloric Acid SCHEMBL28553423 0.98 PRSS1 (0.61) PARP1PRSS1PRSS2PRSS3C1S
Acetic Acid SCHEMBL38652070 0.90 PARP1 (0.63) PARP1PRSS1PRSS2PRSS3C1S
Formic Acid SCHEMBL38652409 0.90 PARP1 (0.58) PARP1PRSS1PRSS2PRSS3C1S
Sulfuric Acid SCHEMBL38652318 0.90 PARP1 (0.58) PARP1PRSS1PRSS2PRSS3C1S
SCHEMBL17774314 0.88 PRSS1 (0.69) PARP1PRSS1PRSS2PRSS3C1S
Trifluoroacetic Acid SCHEMBL38651965 0.84 PARP1 (0.56) PARP1PRSS1PRSS2PRSS3C1S
SCHEMBL15547311 0.83 PRSS1 (0.70) PRSS1PRSS2PRSS3C1SF2
Benzamidine SCHEMBL27905135 0.82 PARP1 (0.58) PARP1PRSS1PRSS2PRSS3C1S
Hydrochloric Acid SCHEMBL28555629 0.80 PRSS1 (0.74) PRSS1PRSS2PRSS3C1SF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010850-A Synthesis method of 3- (5-bromopyrimidinyl) benzyl alcohol 广东莱佛士制药技术有限公司 2026-05-12 — — CN claimed
CN-122010850-A Synthesis method of 3- (5-bromopyrimidinyl) benzyl alcohol 广东莱佛士制药技术有限公司 2026-05-12 — — CN disclosed
US-12595251-B2 Amidines and amidine analogs for the treatment of bacterial infections and potentiation antibiotics GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2026-04-07 — — US disclosed
US-20240150506-A1 CURING AGENTS FOR FLUOROELASTOMERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-05-09 — — US disclosed
EP-4305096-A1 FLUOROELASTOMERS COMPOSITION COMPRISING CURING AGENTS Dupont Specialty Products USA, LLC (US) 2024-01-17 — — EP disclosed
US-20230219896-A1 CANNABINOID RECEPTOR MEDIATING COMPOUNDS THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-07-13 — — US disclosed
US-20230202983-A1 CANNABINOID RECEPTOR MEDIATING COMPOUNDS THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-06-29 — — US disclosed
CN-116324539-A Polarizing plate and image display device 住友化学株式会社 2023-06-23 — — CN disclosed
WO-2023102140-A1 TMPRSS2 INHIBITORS AND METHODS OF USE TOPSPIN THERAPEUTICS, INC. (US) 2023-06-08 — — WO disclosed
WO-2023073115-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-04 — — WO disclosed
WO-2004037176-A2 QUINAZOLINONES AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-05-06 — — WO disclosed
WO-2004031145-A2 LACTAM-CONTAINING DIAMINOALKYL, BETA-AMINOACIDS, ALPHA-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-04-15 — — WO disclosed
US-20030216382-A1 Pyridine and pyrimidine derivatives HOFFMAN-LA ROCHE INC. 2003-11-20 — — US disclosed
WO-2003068757-A1 NOVEL PYRIDIN- AND PYRIMIDIN-DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2003-08-21 — — WO disclosed
WO-2003047520-A2 SUBSTITUTED AMINO METHYL FACTOR Xa INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-06-12 — — WO disclosed
WO-2003048081-A2 GLYCINAMIDES AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-06-12 — — WO disclosed
WO-2003026652-A1 LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-04-03 — — WO disclosed
EP-0132851-B1 5-SUBSTITUTED(1,2,4)TRIAZOLO(1,5-C)PYRIMIDIN-2-AMINES AMERICAN CYANAMID COMPANY (US) 1989-10-04 — — EP disclosed
US-4579848-A ANTIASTHMA AGENTS AMERICAN CYANAMID COMPANY (US) 1986-04-01 — — US disclosed
EP-0132851-A1 5-Substituted(1,2,4)triazolo(1,5-c)pyrimidin-2-amines AMERICAN CYANAMID COMPANY (US) 1985-02-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216382-A1 Pyridine and pyrimidine derivatives DPP4, GPR119, G6PC1 PARP1 923/4885PRSS1 283/4885PRSS2 1024/4885
US-20230219896-A1 CANNABINOID RECEPTOR MEDIATING COMPOUNDS CNR1, CNR2, GPR18 PARP1 1972/4885PRSS1 3403/4885PRSS2 4367/4885
US-20230202983-A1 CANNABINOID RECEPTOR MEDIATING COMPOUNDS CNR1, CNR2, GPR18 PARP1 1972/4885PRSS1 3403/4885PRSS2 4367/4885
US-12595251-B2 Amidines and amidine analogs for the treatment of bacterial infections and potentiation antibiotics CLIC1, CBR3, CBR1 PARP1 3023/4885PRSS1 2532/4885PRSS2 3156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.