Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31635438 | 0.93 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL73473 | 0.89 | ALDH1A1 (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2418727 | 0.88 | SOAT1 (0.44) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2468536 | 0.87 | ALDH1A1 (0.40) | GAAMGAMSIMGAM2ALDH1A1 | |
| Triethyl Citrate SCHEMBL21518137 | 0.86 | GAA (0.43) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL4942630 | 0.86 | PKM (0.40) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL27375665 | 0.85 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL23330 | 0.85 | ALDH1A1 (0.44) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2744420 | 0.84 | ALDH1A1 (0.52) | ALDH1A1EGLN1KDM4EHMGCRCHRM1 | |
| Triethyl Citrate SCHEMBL4250304 | 0.84 | ALDH1A1 (0.52) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168741-B2 | Chelating silicon-based polymers | JOINT INTELLECTUAL PROPERTY POLICY OF MCMASTER UNIVERSITY (CA) | 2012-05-01 | — | — | US | disclosed |
| US-20090118456-A1 | CHELATING SILICON-BASED POLYMERS | MCMASTER UNIVERSITY (CA) | 2009-05-07 | — | — | US | disclosed |
| WO-2008061363-A1 | BIOMOLECULE COMPATIBLE SILICA PARTICLES | MCMASTER UNIVERSITY (CA) | 2008-05-29 | — | — | WO | disclosed |
| EP-1915385-A1 | CHELATING SILICON-BASED POLYMERS | McMaster University (CA) | 2008-04-30 | — | — | EP | disclosed |
| CN-100354126-C | Process for producing cellulose acylate film | FUJIPHOTO FILM CO LTD (JP) | 2007-12-12 | — | — | CN | disclosed |
| US-20070059458-A1 | Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display | FUJI PHOTO FILM CO., LTD. (JP) | 2007-03-15 | — | — | US | disclosed |
| WO-2007014471-A1 | CHELATING SILICON-BASED POLYMERS | MCMASTER UNIVERSITY (CA) | 2007-02-08 | — | — | WO | disclosed |
| CN-1537052-A | Process for producing cellulose acylate film | ��ʿ��Ƭ��ʽ���� | 2004-10-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118456-A1 | CHELATING SILICON-BASED POLYMERS | SRM, SMURF1, SLC39A14 | GAA 109/4885MGAM 2638/4885SI 836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.