Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | WNT3A | P56704 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.54 |
| ▸ | PRKACA | P17612 | 2/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22728453 | 0.80 | MAPT (1.00) | KMT2AMAPTALDH1A1MEN1ESR1 | |
| SCHEMBL14085825 | 0.79 | HDAC1 (0.67) | KMT2AMAPTALDH1A1MEN1POLB | |
| SCHEMBL7929906 | 0.78 | HDAC1 (0.73) | KMT2AMAPTALDH1A1MEN1ESR1 | |
| SCHEMBL21226526 | 0.78 | HDAC1 (0.66) | KMT2AMAPTALDH1A1MEN1ESR1 | |
| SCHEMBL28643881 | 0.78 | HDAC1 (0.66) | KMT2AMAPTALDH1A1MEN1ESR1 | |
| SCHEMBL26884092 | 0.77 | SLC12A2 (0.64) | KMT2AMAPTALDH1A1MEN1POLB | |
| SCHEMBL4420194 | 0.77 | HDAC1 (0.65) | KMT2AMAPTALDH1A1MEN1POLB | |
| SCHEMBL26884098 | 0.76 | WNT3A (0.58) | KMT2AALDH1A1MEN1HDAC1HDAC9 | |
| SCHEMBL10925697 | 0.76 | GSTO1 (0.72) | KMT2AMAPTALDH1A1MEN1ESR1 | |
| SCHEMBL10811295 | 0.76 | GSTO1 (0.72) | KMT2AMAPTALDH1A1MEN1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382903-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS, TOPICAL FORMULATIONS AND METHOD OF USE THEREOF | CARTHRONIX INC (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230382903-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS, TOPICAL FORMULATIONS AND METHOD OF USE THEREOF | CARTHRONIX INC (US) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382903-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS, TOPICAL FORMULATIONS AND METHOD OF USE THEREOF | STAT1, STAT3, STAT6 | KMT2A 4379/4885MAPT 4065/4885ALDH1A1 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.