Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 3/20 | 0.58 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.56 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | CLK1 | P49759 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CDC25A | P30304 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 1/20 | 0.54 |
| ▸ | CDC25C | P30307 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26884092 | 0.85 | SLC12A2 (0.64) | WNT3ASLC12A2SLC12A5HDAC1HDAC9 | |
| SCHEMBL22728498 | 0.81 | LMNA (0.78) | ROCK1KMT2AMEN1LMNACDC25A | |
| SCHEMBL14085825 | 0.78 | HDAC1 (0.67) | HDAC1HDAC9CLK1KMT2AMEN1 | |
| SCHEMBL28643881 | 0.77 | HDAC1 (0.66) | HDAC1HDAC9CLK1KMT2AMEN1 | |
| SCHEMBL21226526 | 0.77 | HDAC1 (0.66) | HDAC1HDAC9CLK1KMT2AMEN1 | |
| SCHEMBL7929906 | 0.77 | HDAC1 (0.73) | HDAC1HDAC9CLK1KMT2AMEN1 | |
| SCHEMBL26884095 | 0.76 | KMT2A (0.67) | WNT3ASLC12A2SLC12A5HDAC1HDAC9 | |
| SCHEMBL21484709 | 0.76 | ABL1 (0.69) | HDAC1HDAC9CLK1KMT2AMEN1 | |
| SCHEMBL12303088 | 0.76 | WNT3A (0.86) | WNT3AROCK1PRKACAKMT2AMEN1 | |
| SCHEMBL4420194 | 0.76 | HDAC1 (0.65) | WNT3AHDAC1HDAC9CLK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382903-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS, TOPICAL FORMULATIONS AND METHOD OF USE THEREOF | CARTHRONIX INC (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230382903-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS, TOPICAL FORMULATIONS AND METHOD OF USE THEREOF | CARTHRONIX INC (US) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382903-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS, TOPICAL FORMULATIONS AND METHOD OF USE THEREOF | STAT1, STAT3, STAT6 | WNT3A 1598/4885SLC12A2 3013/4885SLC12A5 2934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.