Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT5B | Q4FZB7 | 2/20 | 0.39 |
| ▸ | KMT5C | Q86Y97 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26686492 | 0.81 | KDM5B (0.46) | CDC7PIM1CDK9NUDT1AXL | |
| SCHEMBL26686140 | 0.79 | DAO (0.39) | TSHRSMN1; SMN2CDC7PIM1CDK9 | |
| SCHEMBL31240355 | 0.76 | CDK9 (0.41) | HTTGLANPSR1CYP2D6HPGD | |
| SCHEMBL26686776 | 0.74 | HRH3 (0.43) | CYP2D6SMN1; SMN2POLBHRH3CDC7 | |
| SCHEMBL13656931 | 0.74 | ALDH1A1 (0.40) | HTTGLANPSR1CYP2D6HPGD | |
| SCHEMBL16041242 | 0.73 | CSF1R (0.52) | CDK9 | |
| SCHEMBL26889101 | 0.73 | AXL (0.40) | CYP2D6HPGDALDH1A1KDM4ECDC7 | |
| SCHEMBL26889301 | 0.73 | CCNK (0.45) | SMN1; SMN2POLBHRH3CDC7PIM1 | |
| SCHEMBL26889371 | 0.73 | CCNK (0.45) | SMN1; SMN2POLBHRH3CDC7PIM1 | |
| Hydrochloric Acid SCHEMBL4272184 | 0.73 | GLA (0.41) | HTTGLANPSR1CYP2D6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |