Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 7/20 | 0.45 |
| ▸ | CDK12 | Q9NYV4 | 7/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26889338 | 0.86 | CCNK (0.58) | CCNKCDK12CDC7PIM1CDK9 | |
| SCHEMBL26889371 | 0.83 | CCNK (0.45) | CCNKCDK12CDC7PIM1CDK9 | |
| SCHEMBL26889301 | 0.83 | CCNK (0.45) | CCNKCDK12CDC7PIM1CDK9 | |
| SCHEMBL26889381 | 0.82 | CCNK (0.54) | CCNKCDK12HRH4METAP2 | |
| SCHEMBL26686575 | 0.81 | CCNK (0.58) | CCNKCDK12CDC7PIM1CDK9 | |
| SCHEMBL26889310 | 0.79 | CCNK (0.42) | CCNKCDK12CDC7PIM1CDK9 | |
| SCHEMBL26686642 | 0.74 | AXL (0.41) | CCNKCDK12CDC7PIM1CDK9 | |
| SCHEMBL16050712 | 0.73 | CDK9 (0.43) | CDC7PIM1CDK9 | |
| SCHEMBL26889101 | 0.73 | AXL (0.40) | CCNKCDK12CDC7PIM1CDK9 | |
| SCHEMBL26686599 | 0.73 | DRD4 (0.43) | CDK9DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |