Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026405 | 0.89 | LMNA (0.55) | LMNATDP1TSHRF2CYP2D6 | |
| SCHEMBL19749129 | 0.87 | ADRA2C (0.48) | ADRA2CLMNATDP1TSHRF2 | |
| SCHEMBL11850307 | 0.86 | LMNA (0.51) | LMNATDP1TSHRF2CYP2D6 | |
| SCHEMBL27851129 | 0.84 | LMNA (0.50) | LMNATDP1TSHRF2CES2 | |
| SCHEMBL28429762 | 0.83 | CES2 (0.49) | LMNATDP1TSHRCES2CES1 | |
| Hydrochloric Acid SCHEMBL9134016 | 0.78 | LMNA (0.44) | LMNATDP1TSHRCYP2D6CYP1A2 | |
| SCHEMBL4410632 | 0.78 | KMT2A (0.44) | LMNATSHRSMN1; SMN2 | |
| SCHEMBL21559897 | 0.76 | TSHR (0.42) | ADRA2CLMNATDP1TSHRF2 | |
| SCHEMBL1730081 | 0.76 | LMNA (0.53) | LMNATDP1TSHRF2CYP2D6 | |
| SCHEMBL5678485 | 0.74 | LMNA (0.53) | LMNATDP1TSHRF2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225302-A1 | AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2023-11-23 | — | — | WO | disclosed |