SCHEMBL268935

SCHEMBL268935

C=C(C(=O)O)C(C(C(F)(F)F)C(F)(F)F)C(C(F)(F)F)C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL723672 0.74 TET2 (0.32) TET2
SCHEMBL1227973 0.72 TET2 (0.31) TET2
SCHEMBL9715070 0.70 TET2 (0.30) TET2
Itaconate SCHEMBL4307310 0.65 ALOX15 (0.54) TET2
SCHEMBL3137653 0.65 TET2 (0.31) TET2
SCHEMBL3108322 0.64
SCHEMBL2689625 0.63 TET2 (0.33) TET2
SCHEMBL703731 0.63 TET2 (0.33) TET2
SCHEMBL561208 0.63
SCHEMBL6709319 0.62 TET2 (0.36) TET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120288797-A1 PHOTORESIST COMPOSITIONS AND METHODS OF USE IN HIGH INDEX IMMERSION LITHOGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-11-15 US claimed
US-8236482-B2 Photoresist compositions and methods of use in high index immersion lithography INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-08-07 US claimed
US-8133512-B2 Drug delivery systems based on catonic siloxanyl macromonomers BAUSCH & LOMB INCORPORATED (US) 2012-03-13 US claimed
US-8133511-B2 Drug delivery system based on cationic siloxanyl macromonomers BAUSCH & LOMB INCORPORATED (US) 2012-03-13 US claimed
US-20090274745-A1 Drug delivery systems based on catonic siloxanyl macromonomers BAUSCH & LOMB INCORPORATED (US) 2009-11-05 US claimed
US-20090274744-A1 Drug delivery system based on cationic siloxanyl macromonomers BAUSCH & LOMB INCORPORATED (US) 2009-11-05 US claimed
US-7579021-B2 Drug delivery systems based on degradable cationic siloxanyl macromonomers BAUSCH & LOMB INCORPORATED (US) 2009-08-25 US claimed
US-20090181322-A1 Photoresist Compositions and Methods of Use in High Index Immersion Lithography INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-07-16 US claimed
US-7544371-B2 Drug delivery systems BAUSCH + LOMB INCORPORATED (US) 2009-06-09 US claimed
US-20080075780-A1 Drug delivery systems based on degradible cationic siloxanyl macromonomers SANTARUS, INC. 2008-03-27 US claimed
US-20070141115-A1 Drug delivery systems SANTARUS, INC. 2007-06-21 US claimed
US-9250529-B2 Photoresist compositions and methods of use in high index immersion lithography INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2016-02-02 US disclosed
US-20120288797-A1 PHOTORESIST COMPOSITIONS AND METHODS OF USE IN HIGH INDEX IMMERSION LITHOGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-11-15 US disclosed
US-8236482-B2 Photoresist compositions and methods of use in high index immersion lithography INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-08-07 US disclosed
US-8133511-B2 Drug delivery system based on cationic siloxanyl macromonomers BAUSCH & LOMB INCORPORATED (US) 2012-03-13 US disclosed
US-20090181321-A1 Photoresist Compositions and Methods of Use in High Index Immersion Lithography INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-07-16 US disclosed
US-20090181322-A1 Photoresist Compositions and Methods of Use in High Index Immersion Lithography INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-07-16 US disclosed
US-7544371-B2 Drug delivery systems BAUSCH + LOMB INCORPORATED (US) 2009-06-09 US disclosed
US-20080075780-A1 Drug delivery systems based on degradible cationic siloxanyl macromonomers SANTARUS, INC. 2008-03-27 US disclosed
US-20070141115-A1 Drug delivery systems SANTARUS, INC. 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090274744-A1 Drug delivery system based on cationic siloxanyl macromonomers MSR1, LPXN, SRRM2 TET2 2354/4885
US-20090274745-A1 Drug delivery systems based on catonic siloxanyl macromonomers MMP13, LPXN, SLC13A2 TET2 1216/4885
US-20070141115-A1 Drug delivery systems ZYX, SRRM2, MTX1 TET2 3414/4885
US-20080075780-A1 Drug delivery systems based on degradible cationic siloxanyl macromonomers MSR1, LPXN, SRRM2 TET2 1311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.