Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PPID | Q08752 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2690002 | 0.89 | PPID (0.36) | KMT2AATMALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL2689999 | 0.75 | HTT (0.36) | KMT2AMEN1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL31640054 | 0.70 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1ABCB1L3MBTL1 | |
| SCHEMBL4734508 | 0.70 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1ABCB1L3MBTL1 | |
| SCHEMBL1462623 | 0.68 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1ABCB1L3MBTL1 | |
| SCHEMBL1462620 | 0.68 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1ABCB1L3MBTL1 | |
| SCHEMBL18548346 | 0.67 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL27839729 | 0.67 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1ABCB1L3MBTL1 | |
| SCHEMBL27366058 | 0.66 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1ABCB1L3MBTL1 | |
| SCHEMBL17968306 | 0.66 | TDP1 (0.47) | KMT2AMEN1ALDH1A1ABCB1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168741-B2 | Chelating silicon-based polymers | JOINT INTELLECTUAL PROPERTY POLICY OF MCMASTER UNIVERSITY (CA) | 2012-05-01 | — | — | US | disclosed |
| US-20090118456-A1 | CHELATING SILICON-BASED POLYMERS | MCMASTER UNIVERSITY (CA) | 2009-05-07 | — | — | US | disclosed |
| EP-1915385-A1 | CHELATING SILICON-BASED POLYMERS | McMaster University (CA) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007014471-A1 | CHELATING SILICON-BASED POLYMERS | MCMASTER UNIVERSITY (CA) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118456-A1 | CHELATING SILICON-BASED POLYMERS | SRM, SMURF1, SLC39A14 | KMT2A 1571/4885MEN1 2202/4885ATM 3471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.