Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2687930 | 0.91 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL4734515 | 0.86 | ADORA3 (0.39) | ALDH1A1KMT2AMAPK1L3MBTL1NPC1 | |
| SCHEMBL2687931 | 0.80 | CASP1 (0.37) | ALDH1A1KMT2AMAPK1L3MBTL1TGM2 | |
| SCHEMBL2687588 | 0.78 | LMNA (0.37) | ALDH1A1LMNA | |
| SCHEMBL31640054 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1HTTMAPK1 | |
| SCHEMBL20221612 | 0.75 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL15114506 | 0.75 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL1462623 | 0.75 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1HTTMAPK1 | |
| SCHEMBL1462620 | 0.75 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1HTTMAPK1 | |
| SCHEMBL2689999 | 0.74 | HTT (0.36) | ALDH1A1KMT2AMEN1HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061363-A1 | BIOMOLECULE COMPATIBLE SILICA PARTICLES | MCMASTER UNIVERSITY (CA) | 2008-05-29 | — | — | WO | disclosed |