SCHEMBL26910568

SCHEMBL26910568

O=S(=O)(N1CCOCC1)N1CC(c2ccc(F)cc2)CC1CBr

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.39
BRD4 O60885 1/20 0.37
KMT2A Q03164 3/20 0.35
MEN1 O00255 1/20 0.35
PKM P14618 1/20 0.34
LMNA P02545 2/20 0.34
CA12 O43570 1/20 0.34
CA7 P43166 1/20 0.34
CA14 Q9ULX7 1/20 0.34
TP53 P04637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26910574 1.00 SMN1; SMN2 (0.39) SMN1; SMN2BRD4KMT2AMEN1PKM
SCHEMBL26099322 0.88 LMNA (0.40) SMN1; SMN2BRD4KMT2AMEN1PKM
SCHEMBL26100676 0.88 LMNA (0.40) SMN1; SMN2BRD4KMT2AMEN1PKM
SCHEMBL26910518 0.85 FAAH (0.33) ALDH1A1
SCHEMBL26910522 0.85 FAAH (0.33) ALDH1A1
SCHEMBL26097698 0.82 NPC1 (0.40) SMN1; SMN2KMT2AMEN1PKMLMNA
SCHEMBL26098035 0.82 NPC1 (0.40) SMN1; SMN2KMT2AMEN1PKMLMNA
SCHEMBL26532480 0.82 NPC1 (0.40) SMN1; SMN2KMT2AMEN1PKMLMNA
SCHEMBL26098238 0.79 LOX (0.37) SMN1; SMN2TDP1
SCHEMBL26098242 0.79 LOX (0.37) SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12016864-B2 LOX enzyme inhibiting methods and compositions ANOVIA BIOSCIENCES, INC. (US) 2024-06-25 US disclosed
US-20230390299-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES INC (US) 2023-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230390299-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS LOX, LOXL1, LOXL2 SMN1; SMN2 3180/4885BRD4 1577/4885KMT2A 1260/4885
US-12016864-B2 LOX enzyme inhibiting methods and compositions LOX, LOXL1, LOXL2 SMN1; SMN2 1926/4885BRD4 3244/4885KMT2A 1703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.