SCHEMBL269482

SCHEMBL269482

Cc1ccc(C(=O)CC(=O)c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 1.00
RAB9A P51151 6/20 1.00
KMT2A Q03164 4/20 1.00
MEN1 O00255 3/20 1.00
SMN1; SMN2 Q16637 4/20 0.74
MAPT P10636 3/20 0.74
CYP3A4 P08684 3/20 0.74
CES1 P23141 2/20 0.74
HPGD P15428 2/20 0.74
KDM4E B2RXH2 1/20 0.74
ALOX15 P16050 1/20 0.74
MAPK1 P28482 1/20 0.74
TDP1 Q9NUW8 1/20 0.74
CES2 O00748 1/20 0.65
LMNA P02545 1/20 0.63
POLB P06746 1/20 0.63
ALDH1A1 P00352 3/20 0.59
CYP1A2 P05177 2/20 0.59
CYP2C9 P11712 2/20 0.59
PLOD2 O00469 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28972864 0.92 NPC1 (0.85) NPC1RAB9AKMT2AMEN1SMN1; SMN2
SCHEMBL600578 0.91 RAB9A (0.83) NPC1RAB9AKMT2AMEN1SMN1; SMN2
SCHEMBL2005451 0.89 MEN1 (0.94) NPC1RAB9AKMT2AMEN1SMN1; SMN2
SCHEMBL8269520 0.87 KMT2A (0.77) NPC1RAB9AKMT2AMEN1SMN1; SMN2
Dibenzoylmethane SCHEMBL39582 0.86 MEN1 (1.00) NPC1RAB9AKMT2AMEN1SMN1; SMN2
Dibenzoylmethane SCHEMBL10356288 0.86 MEN1 (1.00) NPC1RAB9AKMT2AMEN1SMN1; SMN2
Dibenzoylmethane SCHEMBL1704711 0.86 MEN1 (1.00) NPC1RAB9AKMT2AMEN1SMN1; SMN2
SCHEMBL9349824 0.85 NPC1 (0.73) NPC1RAB9AKMT2AMEN1SMN1; SMN2
SCHEMBL21784396 0.85 NPC1 (0.73) NPC1RAB9AKMT2AMEN1SMN1; SMN2
Toluene SCHEMBL28869912 0.85 KMT2A (0.74) NPC1RAB9AKMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1720 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240173235-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2024-05-30 US claimed
EP-4322915-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS Momentive Performance Materials Inc. (US) 2024-02-21 EP claimed
US-20240026056-A1 PHOTOSTABLE COMPOSITIONS COMPRISING PARA-ALKOXYL PHENYL SUBSTITUTED PROPENOIC ACID (APP) COPOLYMER DERIVATIVES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2024-01-25 US claimed
US-11767392-B2 Photostable compositions comprising para-alkoxyl phenyl substituted propenoic acid (APP) copolymer derivatives HallStar Beauty and Personal Care Innovations Company (US) 2023-09-26 US claimed
WO-2023110777-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE L'OREAL (FR) 2023-06-22 WO claimed
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'OREAL (FR) 2022-07-21 US claimed
CN-114685851-A Photostable compositions comprising p-alkoxyphenyl substituted acrylic Acid (APP) derivatives 浩思特美容与个人护理创新公司 2022-07-01 CN claimed
US-20220017675-A1 Photostable Compositions Comprising Para-Alkoxyl Phenyl Substituted Propenoic Acid (APP) Copolymer Derivatives BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2022-01-20 US claimed
EP-3357483-B1 SUNSCREEN COSMETIC SHISEIDO CO LTD (JP) 2021-01-27 EP claimed
CN-107847422-B Photostable compositions comprising p-alkoxyphenyl substituted acrylic Acid (APP) copolymer derivatives 浩思特美容与个人护理创新公司 2020-11-27 CN claimed
EP-0717982-B1 Process for photostabilizing of dibenzoylmethan derivatives of sunscreen agent, the photostable cosmetic sunscreen compositions and their use OREAL (FR) 1997-07-23 EP claimed
EP-0780119-A1 Light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1997-06-25 EP claimed
EP-0754445-A2 Photostable cosmetic light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1997-01-22 EP claimed
US-5587150-A Photostable cosmetic screening composition containing a UV-A screening agent and an alkyl β, β-diphenylacrylate or α-cyano-β,β-diphenylacrylate L'OREAL (FR) 1996-12-24 US claimed
EP-0748624-A1 Composition containing a dibenzoylmethane derivative and a nanopigment of titanium dioxide and uses thereof L'OREAL (FR) 1996-12-18 EP claimed
US-5576354-A Photostable cosmetic screening composition containing a UV-A screening agent and an alkyl β, β-diphenylacrylate or α-cyano-β,β-diphenylacrylate L'OREAL (FR) 1996-11-19 US claimed
EP-0717982-A1 Process for photostabilizing of dibenzoylmethan derivatives of sunscreen agent, the photostable cosmetic sunscreen compositions and their use L'OREAL (FR) 1996-06-26 EP claimed
EP-0709080-A1 Photostable cosmetic light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1996-05-01 EP claimed
EP-0514491-B1 LIGHT-RESISTANT FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND AN ALKYL BETA, BETA-DIPHENYLACRYLATE OR AN ALKYL ALPHA-CYANO-BETA, BETA-DIPHENYLACRYLATE OREAL (FR) 1993-11-03 EP claimed
WO-1991011989-A1 LIGHT-RESISTANT FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND AN ALKYL β, β-DIPHENYLACRYLATE OR AN ALKYL α-CYANO-β, β-DIPHENYLACRYLATE L'OREAL (FR) 1991-08-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220017675-A1 Photostable Compositions Comprising Para-Alkoxyl Phenyl Substituted Propenoic Acid (APP) Copolymer Derivatives APP, FAP, ANXA5 NPC1 4045/4885RAB9A 3967/4885KMT2A 4029/4885
US-11767392-B2 Photostable compositions comprising para-alkoxyl phenyl substituted propenoic acid (APP) copolymer derivatives APP, FAP, ANXA5 NPC1 4045/4885RAB9A 3967/4885KMT2A 4029/4885
US-20240026056-A1 PHOTOSTABLE COMPOSITIONS COMPRISING PARA-ALKOXYL PHENYL SUBSTITUTED PROPENOIC ACID (APP) COPOLYMER DERIVATIVES APP, FAP, ANXA5 NPC1 4045/4885RAB9A 3967/4885KMT2A 4029/4885
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND ERCC5, DDT, ERCC1 NPC1 2067/4885RAB9A 2771/4885KMT2A 3034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.