Sugi Predict

Sugi Predict / Compounds / SCHEMBL270726

SCHEMBL270726

SCHEMBL270726

Cc1ccc(C(=O)CC(=O)c2ccccc2)c(C)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 10/20 0.71
▸ RAB9A P51151 9/20 0.71
▸ MEN1 O00255 9/20 0.71
▸ NPC1 O15118 8/20 0.71
▸ HSD11B1 P28845 1/20 0.57
▸ SMN1; SMN2 Q16637 7/20 0.57
▸ MAPT P10636 6/20 0.57
▸ HPGD P15428 6/20 0.57
▸ KDM4E B2RXH2 5/20 0.57
▸ ALOX15 P16050 2/20 0.57
▸ MAPK1 P28482 2/20 0.57
▸ CYP3A4 P08684 1/20 0.57
▸ CES1 P23141 1/20 0.57
▸ TDP1 Q9NUW8 1/20 0.57
▸ POLB P06746 1/20 0.54
▸ LMNA P02545 5/20 0.54
▸ HTT P42858 4/20 0.54
▸ NPSR1 Q6W5P4 3/20 0.54
▸ KCNH2 Q12809 2/20 0.54
▸ HSD17B10 Q99714 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7847940 0.94 MEN1 (0.63) KMT2ARAB9AMEN1NPC1HSD11B1
SCHEMBL269145 0.87 MEN1 (0.66) KMT2ARAB9AMEN1NPC1SMN1; SMN2
SCHEMBL7832117 0.85 NPC1 (0.58) KMT2ARAB9AMEN1NPC1SMN1; SMN2
SCHEMBL269482 0.84 NPC1 (1.00) KMT2ARAB9AMEN1NPC1HSD11B1
SCHEMBL268888 0.83 NPC1 (0.70) KMT2ARAB9AMEN1NPC1SMN1; SMN2
SCHEMBL29483365 0.82 ERCC5 (0.68) KMT2ARAB9AMEN1NPC1SMN1; SMN2
SCHEMBL9352393 0.82 HSD11B1 (0.55) KMT2ARAB9AMEN1NPC1HSD11B1
SCHEMBL269381 0.82 ERCC5 (0.68) KMT2ARAB9AMEN1NPC1SMN1; SMN2
SCHEMBL6762644 0.82 RAB9A (0.73) KMT2ARAB9AMEN1NPC1SMN1; SMN2
SCHEMBL11058012 0.79 KMT2A (0.65) KMT2ARAB9AMEN1NPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1907 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4395733-A1 A PHOTOPROTECTIVE PERSONAL CARE COMPOSITION Unilever IP Holdings B.V. (NL) 2024-07-10 — — EP claimed
US-20240173235-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2024-05-30 — — US claimed
CN-117897133-A Photoprotective personal care compositions 联合利华知识产权控股有限公司 2024-04-16 — — CN claimed
EP-4322915-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS Momentive Performance Materials Inc. (US) 2024-02-21 — — EP claimed
CN-117425467-A Personal care compositions comprising silicone based 迈图高新材料公司 2024-01-19 — — CN claimed
WO-2023110777-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE L'OREAL (FR) 2023-06-22 — — WO claimed
WO-2023030963-A1 A PHOTOPROTECTIVE PERSONAL CARE COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2023-03-09 — — WO claimed
CN-110831569-B Photoprotective compositions 欧莱雅 2022-10-21 — — CN claimed
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'OREAL (FR) 2022-07-21 — — US claimed
CN-114699328-A Photoprotective compositions 欧莱雅 2022-07-05 — — CN claimed
EP-0717982-B1 Process for photostabilizing of dibenzoylmethan derivatives of sunscreen agent, the photostable cosmetic sunscreen compositions and their use OREAL (FR) 1997-07-23 — — EP claimed
EP-0780119-A1 Light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1997-06-25 — — EP claimed
EP-0754445-A2 Photostable cosmetic light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1997-01-22 — — EP claimed
US-5587150-A Photostable cosmetic screening composition containing a UV-A screening agent and an alkyl β, β-diphenylacrylate or α-cyano-β,β-diphenylacrylate L'OREAL (FR) 1996-12-24 — — US claimed
EP-0748624-A1 Composition containing a dibenzoylmethane derivative and a nanopigment of titanium dioxide and uses thereof L'OREAL (FR) 1996-12-18 — — EP claimed
US-5576354-A Photostable cosmetic screening composition containing a UV-A screening agent and an alkyl β, β-diphenylacrylate or α-cyano-β,β-diphenylacrylate L'OREAL (FR) 1996-11-19 — — US claimed
EP-0717982-A1 Process for photostabilizing of dibenzoylmethan derivatives of sunscreen agent, the photostable cosmetic sunscreen compositions and their use L'OREAL (FR) 1996-06-26 — — EP claimed
EP-0709080-A1 Photostable cosmetic light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1996-05-01 — — EP claimed
EP-0514491-B1 LIGHT-RESISTANT FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND AN ALKYL BETA, BETA-DIPHENYLACRYLATE OR AN ALKYL ALPHA-CYANO-BETA, BETA-DIPHENYLACRYLATE OREAL (FR) 1993-11-03 — — EP claimed
WO-1991011989-A1 LIGHT-RESISTANT FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND AN ALKYL β, β-DIPHENYLACRYLATE OR AN ALKYL α-CYANO-β, β-DIPHENYLACRYLATE L'OREAL (FR) 1991-08-22 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND ERCC5, DDT, ERCC1 KMT2A 3034/4885RAB9A 2771/4885MEN1 180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.