SCHEMBL7616145

SCHEMBL7616145

COc1ccc(C=NN=Cc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.67
L3MBTL1 Q9Y468 2/20 0.62
LMNA P02545 1/20 0.62
CHRM5 P08912 1/20 0.60
GRIN2D O15399 2/20 0.59
GRIN3B O60391 2/20 0.59
GRIN1 Q05586 2/20 0.59
GRIN2A Q12879 2/20 0.59
GRIN2B Q13224 2/20 0.59
GRIN2C Q14957 2/20 0.59
GRIN3A Q8TCU5 2/20 0.59
RRM1 P23921 1/20 0.56
G6PC1 P35575 1/20 0.56
CA4 P22748 1/20 0.52
CYP1A2 P05177 1/20 0.51
ALDH1A1 P00352 1/20 0.51
RAB9A P51151 4/20 0.50
NPC1 O15118 3/20 0.50
MEN1 O00255 2/20 0.50
GAA P10253 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11776228 0.91 GRIN2D (0.68) TRPA1LMNACHRM5GRIN2DGRIN3B
SCHEMBL269159 0.91 GRIN2D (0.68) TRPA1LMNACHRM5GRIN2DGRIN3B
SCHEMBL8768200 0.84 CHRM5 (0.67) TRPA1L3MBTL1LMNACHRM5GRIN2D
SCHEMBL5718582 0.82 GRIN2D (0.50) TRPA1L3MBTL1LMNACHRM5GRIN2D
SCHEMBL16275197 0.82 S100B (0.71) LMNAGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7792584 0.82 NFE2L2 (0.68) CHRM5GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7792580 0.82 NFE2L2 (0.68) CHRM5GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8495963 0.81 GRIN2D (0.61) TRPA1L3MBTL1LMNAGRIN2DGRIN3B
SCHEMBL699620 0.80 TRPA1 (1.00) TRPA1LMNACYP1A2ALDH1A1RAB9A
SCHEMBL699621 0.80 TRPA1 (1.00) TRPA1LMNACYP1A2ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6433070-B1 COMPRISED OF REPEATING S-TRIAZOLO(1,2-A)-S-TRIAZOLE UNITS; FOR USE IN MAGNETIC RECORDING MEDIA EMTEC MAGNETICS GMBH (DE) 2002-08-13 US disclosed
EP-1185536-A2 HEMISYNTHETIC METHOD AND INTERMEDIATES THEREOF PHARMA MAR, S.A. (ES) 2002-03-13 EP disclosed
EP-1086970-A2 Filler containing binder composition, process for its preparation and its use EMTEC Magnetics GmbH (DE) 2001-03-28 EP disclosed
WO-2000069862-A2 HEMISYNTHETIC METHOD AND INTERMEDIATES THEREOF PHARMA MAR, S.A. (ES) 2000-11-23 WO disclosed
US-4064192-A Heat-stable polyimide resins RHONE-POULENC S.A. (FR) 1977-12-20 US disclosed
US-4039628-A Heat-stable polyimide resins RHONE-POULENC S.A. (FR) 1977-08-02 US disclosed
US-4012361-A Heat-stable polyimide resins from a bis-imide, a polyamine and an alazine RHONE-POULENC S.A. (FR) 1977-03-15 US disclosed
US-3998787-A Heat-stable polyimide resins from bis-imide and aldehyde-azine BARGAIN MICHEL 1976-12-21 US disclosed
US-3972960-A Heat-stable polyimide resin modified by unsaturated polyester RHONE-POULENC S.A. (FR) 1976-08-03 US disclosed
US-3970714-A Heat-stable polyimide resin modified by unsaturated polyester RHONE-POULENC S.A. (FR) 1976-07-20 US disclosed