Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 3/20 | 0.42 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.40 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26918911 | 1.00 | PTK2 (0.42) | PTK2MAPK3MAPK1CDK1CCNB1 | |
| SCHEMBL30697139 | 0.88 | IDH1 (0.44) | PTK2MAPK3MAPK1CDK1CCNB1 | |
| SCHEMBL26919164 | 0.86 | AXL (0.43) | CDK1CCNB1CCNE1CDK2LRRK2 | |
| SCHEMBL26919173 | 0.86 | AXL (0.43) | CDK1CCNB1CCNE1CDK2LRRK2 | |
| SCHEMBL29763036 | 0.86 | AXL (0.43) | CDK1CCNB1CCNE1CDK2LRRK2 | |
| SCHEMBL26920123 | 0.82 | ULK1 (0.44) | PTK2MAPK3MAPK1CDK1CCNB1 | |
| SCHEMBL26920117 | 0.82 | ULK1 (0.44) | PTK2MAPK3MAPK1CDK1CCNB1 | |
| SCHEMBL29763071 | 0.82 | ULK1 (0.44) | PTK2MAPK3MAPK1CDK1CCNB1 | |
| SCHEMBL29763020 | 0.81 | CCR6 (0.42) | MAPK1CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL22998319 | 0.79 | ULK1 (0.44) | PTK2MAPK3MAPK1CDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289835-A1 | CDK INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
| CN-116472270-A | CDK inhibitors | 上海齐鲁制药研究中心有限公司 | 2023-07-21 | — | — | CN | disclosed |